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Urinary NGAL is a useful clinical biomarker of HIV-associated nephropathy.
Sola-Del Valle DA, Mohan S, Cheng JT, Paragas NA, Sise ME, D'Agati VD, Barasch J. Sola-Del Valle DA, et al. Nephrol Dial Transplant. 2011 Jul;26(7):2387-90. doi: 10.1093/ndt/gfr258. Epub 2011 May 9. Nephrol Dial Transplant. 2011. PMID: 21555394 Free PMC article.
Scara5 is a ferritin receptor mediating non-transferrin iron delivery.
Li JY, Paragas N, Ned RM, Qiu A, Viltard M, Leete T, Drexler IR, Chen X, Sanna-Cherchi S, Mohammed F, Williams D, Lin CS, Schmidt-Ott KM, Andrews NC, Barasch J. Li JY, et al. Dev Cell. 2009 Jan;16(1):35-46. doi: 10.1016/j.devcel.2008.12.002. Dev Cell. 2009. PMID: 19154717 Free PMC article.
Mutations in transcription factor CP2-like 1 may cause a novel syndrome with distal renal tubulopathy in humans.
Klämbt V, Werth M, Onuchic-Whitford AC, Getwan M, Kitzler TM, Buerger F, Mao Y, Deutsch K, Mann N, Majmundar AJ, Kaminski MM, Shen T, Schmidt-Ott KM, Shalaby M, El Desoky S, Kari JA, Shril S, Lienkamp SS, Barasch J, Hildebrandt F. Klämbt V, et al. Nephrol Dial Transplant. 2021 Jan 25;36(2):237-246. doi: 10.1093/ndt/gfaa215. Nephrol Dial Transplant. 2021. PMID: 33097957 Free PMC article.
The Ngal reporter mouse detects the response of the kidney to injury in real time.
Paragas N, Qiu A, Zhang Q, Samstein B, Deng SX, Schmidt-Ott KM, Viltard M, Yu W, Forster CS, Gong G, Liu Y, Kulkarni R, Mori K, Kalandadze A, Ratner AJ, Devarajan P, Landry DW, D'Agati V, Lin CS, Barasch J. Paragas N, et al. Nat Med. 2011 Feb;17(2):216-22. doi: 10.1038/nm.2290. Epub 2011 Jan 16. Nat Med. 2011. PMID: 21240264 Free PMC article.
Urinary NGAL marks cystic disease in HIV-associated nephropathy.
Paragas N, Nickolas TL, Wyatt C, Forster CS, Sise M, Morgello S, Jagla B, Buchen C, Stella P, Sanna-Cherchi S, Carnevali ML, Mattei S, Bovino A, Argentiero L, Magnano A, Devarajan P, Schmidt-Ott KM, Allegri L, Klotman P, D'Agati V, Gharavi AG, Barasch J. Paragas N, et al. J Am Soc Nephrol. 2009 Aug;20(8):1687-92. doi: 10.1681/ASN.2009010065. Epub 2009 Jul 23. J Am Soc Nephrol. 2009. PMID: 19628667 Free PMC article.
Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex.
Bao G, Clifton M, Hoette TM, Mori K, Deng SX, Qiu A, Viltard M, Williams D, Paragas N, Leete T, Kulkarni R, Li X, Lee B, Kalandadze A, Ratner AJ, Pizarro JC, Schmidt-Ott KM, Landry DW, Raymond KN, Strong RK, Barasch J. Bao G, et al. Nat Chem Biol. 2010 Aug;6(8):602-9. doi: 10.1038/nchembio.402. Epub 2010 Jun 27. Nat Chem Biol. 2010. PMID: 20581821 Free PMC article.
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