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Page 1
Microenvironmental Control of Adipocyte Fate and Function.
Pope BD, Warren CR, Parker KK, Cowan CA. Pope BD, et al. Trends Cell Biol. 2016 Oct;26(10):745-755. doi: 10.1016/j.tcb.2016.05.005. Epub 2016 Jun 4. Trends Cell Biol. 2016. PMID: 27268909 Free PMC article. Review.
Mitoregulin Controls β-Oxidation in Human and Mouse Adipocytes.
Friesen M, Warren CR, Yu H, Toyohara T, Ding Q, Florido MHC, Sayre C, Pope BD, Goff LA, Rinn JL, Cowan CA. Friesen M, et al. Stem Cell Reports. 2020 Apr 14;14(4):590-602. doi: 10.1016/j.stemcr.2020.03.002. Epub 2020 Apr 2. Stem Cell Reports. 2020. PMID: 32243843 Free PMC article.
White-to-brown metabolic conversion of human adipocytes by JAK inhibition.
Moisan A, Lee YK, Zhang JD, Hudak CS, Meyer CA, Prummer M, Zoffmann S, Truong HH, Ebeling M, Kiialainen A, Gérard R, Xia F, Schinzel RT, Amrein KE, Cowan CA. Moisan A, et al. Nat Cell Biol. 2015 Jan;17(1):57-67. doi: 10.1038/ncb3075. Epub 2014 Dec 8. Nat Cell Biol. 2015. PMID: 25487280 Free PMC article.
Programming human pluripotent stem cells into white and brown adipocytes.
Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA. Ahfeldt T, et al. Nat Cell Biol. 2012 Jan 15;14(2):209-19. doi: 10.1038/ncb2411. Nat Cell Biol. 2012. PMID: 22246346 Free PMC article.
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.
Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE. Roberts LD, et al. Cell Metab. 2014 Jan 7;19(1):96-108. doi: 10.1016/j.cmet.2013.12.003. Cell Metab. 2014. PMID: 24411942 Free PMC article. Clinical Trial.
A TALEN genome-editing system for generating human stem cell-based disease models.
Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA. Ding Q, et al. Cell Stem Cell. 2013 Feb 7;12(2):238-51. doi: 10.1016/j.stem.2012.11.011. Epub 2012 Dec 13. Cell Stem Cell. 2013. PMID: 23246482 Free PMC article.