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2015 1
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28 results

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Page 1
The many lives of Myc in the pancreatic β-cell.
Rosselot C, Baumel-Alterzon S, Li Y, Brill G, Lambertini L, Katz LS, Lu G, Garcia-Ocaña A, Scott DK. Rosselot C, et al. J Biol Chem. 2021 Jan-Jun;296:100122. doi: 10.1074/jbc.REV120.011149. Epub 2020 Dec 2. J Biol Chem. 2021. PMID: 33239359 Free PMC article. Review.
GLP-1 receptor agonists synergize with DYRK1A inhibitors to potentiate functional human β cell regeneration.
Ackeifi C, Wang P, Karakose E, Manning Fox JE, González BJ, Liu H, Wilson J, Swartz E, Berrouet C, Li Y, Kumar K, MacDonald PE, Sanchez R, Thorens B, DeVita R, Homann D, Egli D, Scott DK, Garcia-Ocaña A, Stewart AF. Ackeifi C, et al. Sci Transl Med. 2020 Feb 12;12(530):eaaw9996. doi: 10.1126/scitranslmed.aaw9996. Sci Transl Med. 2020. PMID: 32051230 Free PMC article.
Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.
Katz LS, Brill G, Zhang P, Kumar A, Baumel-Alterzon S, Honig LB, Gómez-Banoy N, Karakose E, Tanase M, Doridot L, Alvarsson A, Davenport B, Wang P, Lambertini L, Stanley SA, Homann D, Stewart AF, Lo JC, Herman MA, Garcia-Ocaña A, Scott DK. Katz LS, et al. Nat Commun. 2022 Jul 30;13(1):4423. doi: 10.1038/s41467-022-32162-x. Nat Commun. 2022. PMID: 35908073 Free PMC article.
Nrf2: The Master and Captain of Beta Cell Fate.
Baumel-Alterzon S, Katz LS, Brill G, Garcia-Ocaña A, Scott DK. Baumel-Alterzon S, et al. Trends Endocrinol Metab. 2021 Jan;32(1):7-19. doi: 10.1016/j.tem.2020.11.002. Epub 2020 Nov 23. Trends Endocrinol Metab. 2021. PMID: 33243626 Free PMC article. Review.
Advances in drug discovery for human beta cell regeneration.
Karakose E, Ackeifi C, Wang P, Stewart AF. Karakose E, et al. Diabetologia. 2018 Aug;61(8):1693-1699. doi: 10.1007/s00125-018-4639-6. Epub 2018 May 16. Diabetologia. 2018. PMID: 29770834 Free PMC article. Review.
Disrupting the DREAM complex enables proliferation of adult human pancreatic β cells.
Wang P, Karakose E, Argmann C, Wang H, Balev M, Brody RI, Rivas HG, Liu X, Wood O, Liu H, Choleva L, Hasson D, Bernstein E, Paulo JA, Scott DK, Lambertini L, DeCaprio JA, Stewart AF. Wang P, et al. J Clin Invest. 2022 Aug 1;132(15):e157086. doi: 10.1172/JCI157086. J Clin Invest. 2022. PMID: 35700053 Free PMC article.
Replication confers β cell immaturity.
Puri S, Roy N, Russ HA, Leonhardt L, French EK, Roy R, Bengtsson H, Scott DK, Stewart AF, Hebrok M. Puri S, et al. Nat Commun. 2018 Feb 2;9(1):485. doi: 10.1038/s41467-018-02939-0. Nat Commun. 2018. PMID: 29396395 Free PMC article.
28 results