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Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy.
Biochem Soc Trans. 2007 Feb;35(Pt 1):12-7. doi: 10.1042/BST0350012.
Biochem Soc Trans. 2007.
PMID: 17212580
Review.
On prions, proteasomes, and mad cows.
Goldberg AL.
Goldberg AL.
N Engl J Med. 2007 Sep 13;357(11):1150-2. doi: 10.1056/NEJMcibr073962.
N Engl J Med. 2007.
PMID: 17855677
No abstract available.
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Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.
Kim HT, Kim KP, Lledias F, Kisselev AF, Scaglione KM, Skowyra D, Gygi SP, Goldberg AL.
Kim HT, et al.
J Biol Chem. 2007 Jun 15;282(24):17375-86. doi: 10.1074/jbc.M609659200. Epub 2007 Apr 10.
J Biol Chem. 2007.
PMID: 17426036
Free article.
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ATP-induced structural transitions in PAN, the proteasome-regulatory ATPase complex in Archaea.
Horwitz AA, Navon A, Groll M, Smith DM, Reis C, Goldberg AL.
Horwitz AA, et al.
J Biol Chem. 2007 Aug 3;282(31):22921-9. doi: 10.1074/jbc.M702846200. Epub 2007 Jun 6.
J Biol Chem. 2007.
PMID: 17553803
Free article.
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Puromycin-sensitive aminopeptidase is the major peptidase responsible for digesting polyglutamine sequences released by proteasomes during protein degradation.
Bhutani N, Venkatraman P, Goldberg AL.
Bhutani N, et al.
EMBO J. 2007 Mar 7;26(5):1385-96. doi: 10.1038/sj.emboj.7601592. Epub 2007 Feb 22.
EMBO J. 2007.
PMID: 17318184
Free PMC article.
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