R01 GM066170/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2004	1
2005	1
2006	1
2008	1
2009	7
2010	7
2011	13
2012	11
2013	8
2014	4
2015	7
2016	7
2017	5
2018	3
2019	1
2024	0

1

Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.

Robichaux WG 3rd, Cheng X. Robichaux WG 3rd, et al. Physiol Rev. 2018 Apr 1;98(2):919-1053. doi: 10.1152/physrev.00025.2017. Physiol Rev. 2018. PMID: 29537337 Free PMC article. Review.

2

Cyclic AMP sensor EPAC proteins and energy homeostasis.

Almahariq M, Mei FC, Cheng X. Almahariq M, et al. Trends Endocrinol Metab. 2014 Feb;25(2):60-71. doi: 10.1016/j.tem.2013.10.004. Epub 2013 Nov 12. Trends Endocrinol Metab. 2014. PMID: 24231725 Free PMC article. Review.

3

Exchange proteins directly activated by cAMP (EPACs): Emerging therapeutic targets.

Wang P, Liu Z, Chen H, Ye N, Cheng X, Zhou J. Wang P, et al. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1633-1639. doi: 10.1016/j.bmcl.2017.02.065. Epub 2017 Feb 27. Bioorg Med Chem Lett. 2017. PMID: 28283242 Free PMC article. Review.

4

Epac and PKA: a tale of two intracellular cAMP receptors.

Cheng X, Ji Z, Tsalkova T, Mei F. Cheng X, et al. Acta Biochim Biophys Sin (Shanghai). 2008 Jul;40(7):651-62. doi: 10.1111/j.1745-7270.2008.00438.x. Acta Biochim Biophys Sin (Shanghai). 2008. PMID: 18604457 Free PMC article. Review.

5

Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).

Chen H, Wild C, Zhou X, Ye N, Cheng X, Zhou J. Chen H, et al. J Med Chem. 2014 May 8;57(9):3651-65. doi: 10.1021/jm401425e. Epub 2013 Nov 27. J Med Chem. 2014. PMID: 24256330 Free PMC article. Review.

6

Microtubule-regulating proteins and cAMP-dependent signaling in neuroblastoma differentiation.

Muñoz-Llancao P, de Gregorio C, Las Heras M, Meinohl C, Noorman K, Boddeke E, Cheng X, Lezoualc'h F, Schmidt M, Gonzalez-Billault C. Muñoz-Llancao P, et al. Cytoskeleton (Hoboken). 2017 Mar;74(3):143-158. doi: 10.1002/cm.21355. Epub 2017 Feb 13. Cytoskeleton (Hoboken). 2017. PMID: 28164467

7

The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention.

Almahariq M, Mei FC, Cheng X. Almahariq M, et al. Acta Biochim Biophys Sin (Shanghai). 2016 Jan;48(1):75-81. doi: 10.1093/abbs/gmv115. Epub 2015 Nov 2. Acta Biochim Biophys Sin (Shanghai). 2016. PMID: 26525949 Free PMC article. Review.

8

Structural basis for differential neutralization of ebolaviruses.

Bale S, Dias JM, Fusco ML, Hashiguchi T, Wong AC, Liu T, Keuhne AI, Li S, Woods VL Jr, Chandran K, Dye JM, Saphire EO. Bale S, et al. Viruses. 2012 Apr;4(4):447-70. doi: 10.3390/v4040447. Epub 2012 Apr 5. Viruses. 2012. PMID: 22590681 Free PMC article. Review.

9

Identification of novel 2-(benzo[d]isoxazol-3-yl)-2-oxo-N-phenylacetohydrazonoyl cyanide analoguesas potent EPAC antagonists.

Ye N, Zhu Y, Liu Z, Mei FC, Chen H, Wang P, Cheng X, Zhou J. Ye N, et al. Eur J Med Chem. 2017 Jul 7;134:62-71. doi: 10.1016/j.ejmech.2017.04.001. Epub 2017 Apr 4. Eur J Med Chem. 2017. PMID: 28399451 Free PMC article.

10

Urinary concentrating defect in mice lacking Epac1 or Epac2.

Cherezova A, Tomilin V, Buncha V, Zaika O, Ortiz PA, Mei F, Cheng X, Mamenko M, Pochynyuk O. Cherezova A, et al. FASEB J. 2019 Feb;33(2):2156-2170. doi: 10.1096/fj.201800435R. Epub 2018 Sep 25. FASEB J. 2019. PMID: 30252533 Free PMC article.

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