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Isoform-selective histone deacetylase inhibitors.
Chem Soc Rev. 2008 Jul;37(7):1402-13. doi: 10.1039/b703830p. Epub 2008 May 8.
Chem Soc Rev. 2008.
PMID: 18568166
Free PMC article.
Review.
Synthesis and biological evaluation of histone deacetylase inhibitors that are based on FR235222: a cyclic tetrapeptide scaffold.
Singh EK, Ravula S, Pan CM, Pan PS, Vasko RC, Lapera SA, Weerasinghe SV, Pflum MK, McAlpine SR.
Singh EK, et al.
Bioorg Med Chem Lett. 2008 Apr 15;18(8):2549-54. doi: 10.1016/j.bmcl.2008.03.047. Epub 2008 Mar 20.
Bioorg Med Chem Lett. 2008.
PMID: 18381239
Free PMC article.
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Residues in the 11 A channel of histone deacetylase 1 promote catalytic activity: implications for designing isoform-selective histone deacetylase inhibitors.
Weerasinghe SV, Estiu G, Wiest O, Pflum MK.
Weerasinghe SV, et al.
J Med Chem. 2008 Sep 25;51(18):5542-51. doi: 10.1021/jm800081j. Epub 2008 Aug 27.
J Med Chem. 2008.
PMID: 18729444
Free PMC article.
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