R01 GM076477/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2007	1
2008	2
2009	5
2010	4
2011	4
2012	2
2013	3
2014	3
2015	4
2016	3
2017	4
2018	2
2024	0

1

Frontiers and opportunities in chemoenzymatic synthesis.

Mortison JD, Sherman DH. Mortison JD, et al. J Org Chem. 2010 Nov 5;75(21):7041-51. doi: 10.1021/jo101124n. J Org Chem. 2010. PMID: 20882949 Free PMC article. Review.

2

Architecture of the polyketide synthase module: surprises from electron cryo-microscopy.

Smith JL, Skiniotis G, Sherman DH. Smith JL, et al. Curr Opin Struct Biol. 2015 Apr;31:9-19. doi: 10.1016/j.sbi.2015.02.014. Epub 2015 Mar 16. Curr Opin Struct Biol. 2015. PMID: 25791608 Free PMC article. Review.

3

PKS-NRPS Enzymology and Structural Biology: Considerations in Protein Production.

Skiba MA, Maloney FP, Dan Q, Fraley AE, Aldrich CC, Smith JL, Brown WC. Skiba MA, et al. Methods Enzymol. 2018;604:45-88. doi: 10.1016/bs.mie.2018.01.035. Epub 2018 Mar 16. Methods Enzymol. 2018. PMID: 29779664 Free PMC article.

4

Automated genome mining for natural products.

Li MH, Ung PM, Zajkowski J, Garneau-Tsodikova S, Sherman DH. Li MH, et al. BMC Bioinformatics. 2009 Jun 16;10:185. doi: 10.1186/1471-2105-10-185. BMC Bioinformatics. 2009. PMID: 19531248 Free PMC article.

5

Substrate controlled divergence in polyketide synthase catalysis.

Hansen DA, Koch AA, Sherman DH. Hansen DA, et al. J Am Chem Soc. 2015 Mar 25;137(11):3735-8. doi: 10.1021/ja511743n. Epub 2015 Mar 12. J Am Chem Soc. 2015. PMID: 25730816 Free PMC article.

6

Structure of a modular polyketide synthase.

Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G. Dutta S, et al. Nature. 2014 Jun 26;510(7506):512-7. doi: 10.1038/nature13423. Epub 2014 Jun 18. Nature. 2014. PMID: 24965652 Free PMC article.

7

Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.

Hansen DA, Rath CM, Eisman EB, Narayan AR, Kittendorf JD, Mortison JD, Yoon YJ, Sherman DH. Hansen DA, et al. J Am Chem Soc. 2013 Jul 31;135(30):11232-8. doi: 10.1021/ja404134f. Epub 2013 Jul 18. J Am Chem Soc. 2013. PMID: 23866020 Free PMC article.

8

Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination.

Chemler JA, Tripathi A, Hansen DA, O'Neil-Johnson M, Williams RB, Starks C, Park SR, Sherman DH. Chemler JA, et al. J Am Chem Soc. 2015 Aug 26;137(33):10603-9. doi: 10.1021/jacs.5b04842. Epub 2015 Aug 13. J Am Chem Soc. 2015. PMID: 26230368 Free PMC article.

9

Identification of a Thioesterase Bottleneck in the Pikromycin Pathway through Full-Module Processing of Unnatural Pentaketides.

Hansen DA, Koch AA, Sherman DH. Hansen DA, et al. J Am Chem Soc. 2017 Sep 27;139(38):13450-13455. doi: 10.1021/jacs.7b06432. Epub 2017 Sep 19. J Am Chem Soc. 2017. PMID: 28836772 Free PMC article.

10

Chemoenzymatic Dissection of Polyketide β-Branching in the Bryostatin Pathway.

Slocum ST, Lowell AN, Tripathi A, Shende VV, Smith JL, Sherman DH. Slocum ST, et al. Methods Enzymol. 2018;604:207-236. doi: 10.1016/bs.mie.2018.01.034. Epub 2018 Apr 9. Methods Enzymol. 2018. PMID: 29779653 Free PMC article.

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