R01 GM108803/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2014	1
2015	4
2016	6
2017	7
2018	4
2019	3
2024	0

1

The chemical evolution of oligonucleotide therapies of clinical utility.

Khvorova A, Watts JK. Khvorova A, et al. Nat Biotechnol. 2017 Mar;35(3):238-248. doi: 10.1038/nbt.3765. Epub 2017 Feb 27. Nat Biotechnol. 2017. PMID: 28244990 Free PMC article. Review.

2

Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo.

Biscans A, Coles A, Haraszti R, Echeverria D, Hassler M, Osborn M, Khvorova A. Biscans A, et al. Nucleic Acids Res. 2019 Feb 20;47(3):1082-1096. doi: 10.1093/nar/gky1239. Nucleic Acids Res. 2019. PMID: 30544191 Free PMC article.

3

Oligonucleotide Therapeutics - A New Class of Cholesterol-Lowering Drugs.

Khvorova A. Khvorova A. N Engl J Med. 2017 Jan 5;376(1):4-7. doi: 10.1056/NEJMp1614154. N Engl J Med. 2017. PMID: 28052224 No abstract available.

4

Editorial: Nucleic Acids Research and Nucleic Acid Therapeutics.

Stoddard BL, Khvorova A, Corey DR, Dynan WS, Fox KR. Stoddard BL, et al. Nucleic Acids Res. 2018 Feb 28;46(4):1563-1564. doi: 10.1093/nar/gky059. Nucleic Acids Res. 2018. PMID: 29506274 Free PMC article. No abstract available.

5

Voices of biotech.

Amit I, Baker D, Barker R, Berger B, Bertozzi C, Bhatia S, Biffi A, Demichelis F, Doudna J, Dowdy SF, Endy D, Helmstaedter M, Junca H, June C, Kamb S, Khvorova A, Kim DH, Kim JS, Krishnan Y, Lakadamyali M, Lappalainen T, Lewin S, Liao J, Loman N, Lundberg E, Lynd L, Martin C, Mellman I, Miyawaki A, Mummery C, Nelson K, Paz J, Peralta-Yahya P, Picotti P, Polyak K, Prather K, Qin J, Quake S, Regev A, Rogers JA, Shetty R, Sommer M, Stevens M, Stolovitzky G, Takahashi M, Tang F, Teichmann S, Torres-Padilla ME, Tripathi L, Vemula P, Verdine G, Vollmer F, Wang J, Ying JY, Zhang F, Zhang T. Amit I, et al. Nat Biotechnol. 2016 Mar;34(3):270-5. doi: 10.1038/nbt.3502. Nat Biotechnol. 2016. PMID: 26963549 No abstract available.

6

Efficient Gene Silencing in Brain Tumors with Hydrophobically Modified siRNAs.

Osborn MF, Coles AH, Golebiowski D, Echeverria D, Moazami MP, Watts JK, Sena-Esteves M, Khvorova A. Osborn MF, et al. Mol Cancer Ther. 2018 Jun;17(6):1251-1258. doi: 10.1158/1535-7163.MCT-17-1144. Epub 2018 Apr 13. Mol Cancer Ther. 2018. PMID: 29654062 Free PMC article.

7

High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources.

Haraszti RA, Didiot MC, Sapp E, Leszyk J, Shaffer SA, Rockwell HE, Gao F, Narain NR, DiFiglia M, Kiebish MA, Aronin N, Khvorova A. Haraszti RA, et al. J Extracell Vesicles. 2016 Nov 17;5:32570. doi: 10.3402/jev.v5.32570. eCollection 2016. J Extracell Vesicles. 2016. PMID: 27863537 Free PMC article.

8

Visualization of self-delivering hydrophobically modified siRNA cellular internalization.

Ly S, Navaroli DM, Didiot MC, Cardia J, Pandarinathan L, Alterman JF, Fogarty K, Standley C, Lifshitz LM, Bellve KD, Prot M, Echeverria D, Corvera S, Khvorova A. Ly S, et al. Nucleic Acids Res. 2017 Jan 9;45(1):15-25. doi: 10.1093/nar/gkw1005. Epub 2016 Nov 28. Nucleic Acids Res. 2017. PMID: 27899655 Free PMC article.

9

Taking charge of siRNA delivery.

Khvorova A, Osborn MF, Hassler MR. Khvorova A, et al. Nat Biotechnol. 2014 Dec;32(12):1197-8. doi: 10.1038/nbt.3091. Nat Biotechnol. 2014. PMID: 25489835

10

5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo.

Haraszti RA, Roux L, Coles AH, Turanov AA, Alterman JF, Echeverria D, Godinho BMDC, Aronin N, Khvorova A. Haraszti RA, et al. Nucleic Acids Res. 2017 Jul 27;45(13):7581-7592. doi: 10.1093/nar/gkx507. Nucleic Acids Res. 2017. PMID: 28591791 Free PMC article.

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