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A lifelong duty: how Xist maintains the inactive X chromosome.
Jacobson EC, Pandya-Jones A, Plath K. Jacobson EC, et al. Curr Opin Genet Dev. 2022 Aug;75:101927. doi: 10.1016/j.gde.2022.101927. Epub 2022 Jun 16. Curr Opin Genet Dev. 2022. PMID: 35717799 Free PMC article. Review.
RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding.
Zacco E, Broglia L, Kurihara M, Monti M, Gustincich S, Pastore A, Plath K, Nagakawa S, Cerase A, Sanchez de Groot N, Tartaglia GG. Zacco E, et al. Chem Rev. 2024 Apr 24;124(8):4734-4777. doi: 10.1021/acs.chemrev.3c00575. Epub 2024 Apr 5. Chem Rev. 2024. PMID: 38579177 Free PMC article. Review.
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids.
Watanabe M, Buth JE, Haney JR, Vishlaghi N, Turcios F, Elahi LS, Gu W, Pearson CA, Kurdian A, Baliaouri NV, Collier AJ, Miranda OA, Dunn N, Chen D, Sabri S, Torre-Ubieta L, Clark AT, Plath K, Christofk HR, Kornblum HI, Gandal MJ, Novitch BG. Watanabe M, et al. Stem Cell Reports. 2022 Oct 11;17(10):2220-2238. doi: 10.1016/j.stemcr.2022.08.013. Epub 2022 Sep 29. Stem Cell Reports. 2022. PMID: 36179695 Free PMC article.
Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naïve pluripotent cell reprogramming.
Collier AJ, Bendall A, Fabian C, Malcolm AA, Tilgner K, Semprich CI, Wojdyla K, Nisi PS, Kishore K, Roamio Franklin VN, Mirshekar-Syahkal B, D'Santos C, Plath K, Yusa K, Rugg-Gunn PJ. Collier AJ, et al. Sci Adv. 2022 Mar 25;8(12):eabk0013. doi: 10.1126/sciadv.abk0013. Epub 2022 Mar 25. Sci Adv. 2022. PMID: 35333572 Free PMC article.