R01 HG008688/HG/NHGRI NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	3
2017	6
2018	5
2019	1
2020	1
2021	1
2022	1
2024	0

1

Post-transcriptional gene regulation by mRNA modifications.

Zhao BS, Roundtree IA, He C. Zhao BS, et al. Nat Rev Mol Cell Biol. 2017 Jan;18(1):31-42. doi: 10.1038/nrm.2016.132. Epub 2016 Nov 3. Nat Rev Mol Cell Biol. 2017. PMID: 27808276 Free PMC article. Review.

2

Mettl3-/Mettl14-mediated mRNA N⁶-methyladenosine modulates murine spermatogenesis.

Lin Z, Hsu PJ, Xing X, Fang J, Lu Z, Zou Q, Zhang KJ, Zhang X, Zhou Y, Zhang T, Zhang Y, Song W, Jia G, Yang X, He C, Tong MH. Lin Z, et al. Cell Res. 2017 Oct;27(10):1216-1230. doi: 10.1038/cr.2017.117. Epub 2017 Sep 15. Cell Res. 2017. PMID: 28914256 Free PMC article.

3

YTHDC1 mediates nuclear export of N⁶-methyladenosine methylated mRNAs.

Roundtree IA, Luo GZ, Zhang Z, Wang X, Zhou T, Cui Y, Sha J, Huang X, Guerrero L, Xie P, He E, Shen B, He C. Roundtree IA, et al. Elife. 2017 Oct 6;6:e31311. doi: 10.7554/eLife.31311. Elife. 2017. PMID: 28984244 Free PMC article.

4

Zc3h13 Regulates Nuclear RNA m⁶A Methylation and Mouse Embryonic Stem Cell Self-Renewal.

Wen J, Lv R, Ma H, Shen H, He C, Wang J, Jiao F, Liu H, Yang P, Tan L, Lan F, Shi YG, He C, Shi Y, Diao J. Wen J, et al. Mol Cell. 2018 Mar 15;69(6):1028-1038.e6. doi: 10.1016/j.molcel.2018.02.015. Mol Cell. 2018. PMID: 29547716 Free PMC article.

5

m⁶A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.

Liu J, Eckert MA, Harada BT, Liu SM, Lu Z, Yu K, Tienda SM, Chryplewicz A, Zhu AC, Yang Y, Huang JT, Chen SM, Xu ZG, Leng XH, Yu XC, Cao J, Zhang Z, Liu J, Lengyel E, He C. Liu J, et al. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27. Nat Cell Biol. 2018. PMID: 30154548 Free PMC article.

6

VIRMA mediates preferential m⁶A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation.

Yue Y, Liu J, Cui X, Cao J, Luo G, Zhang Z, Cheng T, Gao M, Shu X, Ma H, Wang F, Wang X, Shen B, Wang Y, Feng X, He C, Liu J. Yue Y, et al. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018. Cell Discov. 2018. PMID: 29507755 Free PMC article.

7

The emerging biology of RNA post-transcriptional modifications.

Nachtergaele S, He C. Nachtergaele S, et al. RNA Biol. 2017 Feb;14(2):156-163. doi: 10.1080/15476286.2016.1267096. Epub 2016 Dec 12. RNA Biol. 2017. PMID: 27937535 Free PMC article. Review.

8

5-methylcytosine (m⁵C) RNA modification controls the innate immune response to virus infection by regulating type I interferons.

Zhang Y, Zhang LS, Dai Q, Chen P, Lu M, Kairis EL, Murugaiah V, Xu J, Shukla RK, Liang X, Zou Z, Cormet-Boyaka E, Qiu J, Peeples ME, Sharma A, He C, Li J. Zhang Y, et al. Proc Natl Acad Sci U S A. 2022 Oct 18;119(42):e2123338119. doi: 10.1073/pnas.2123338119. Epub 2022 Oct 14. Proc Natl Acad Sci U S A. 2022. PMID: 36240321 Free PMC article.

9

m⁶A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition.

Zhao BS, Wang X, Beadell AV, Lu Z, Shi H, Kuuspalu A, Ho RK, He C. Zhao BS, et al. Nature. 2017 Feb 23;542(7642):475-478. doi: 10.1038/nature21355. Epub 2017 Feb 13. Nature. 2017. PMID: 28192787 Free PMC article.

10

N⁶-methyladenosine (m⁶A) recruits and repels proteins to regulate mRNA homeostasis.

Edupuganti RR, Geiger S, Lindeboom RGH, Shi H, Hsu PJ, Lu Z, Wang SY, Baltissen MPA, Jansen PWTC, Rossa M, Müller M, Stunnenberg HG, He C, Carell T, Vermeulen M. Edupuganti RR, et al. Nat Struct Mol Biol. 2017 Oct;24(10):870-878. doi: 10.1038/nsmb.3462. Epub 2017 Sep 4. Nat Struct Mol Biol. 2017. PMID: 28869609 Free PMC article.

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