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Novel interactions between NFATc1 (Nuclear Factor of Activated T cells c1) and STAT-3 (Signal Transducer and Activator of Transcription-3) mediate G protein-coupled receptor agonist, thrombin-induced biphasic expression of cyclin D1, with first phase influencing cell migration and second phase directing cell proliferation.
Kundumani-Sridharan V, Van Quyen D, Subramani J, Singh NK, Chin YE, Rao GN. Kundumani-Sridharan V, et al. J Biol Chem. 2012 Jun 29;287(27):22463-82. doi: 10.1074/jbc.M112.362996. Epub 2012 May 6. J Biol Chem. 2012. PMID: 22566696 Free PMC article.
Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration, and proliferation and injury-induced vascular wall remodeling.
Kundumani-Sridharan V, Singh NK, Kumar S, Gadepalli R, Rao GN. Kundumani-Sridharan V, et al. J Biol Chem. 2013 Jul 26;288(30):22150-62. doi: 10.1074/jbc.M113.454082. Epub 2013 Jun 4. J Biol Chem. 2013. PMID: 23737530 Free PMC article.
16 results