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The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk.
Deming Y, Filipello F, Cignarella F, Cantoni C, Hsu S, Mikesell R, Li Z, Del-Aguila JL, Dube U, Farias FG, Bradley J, Budde J, Ibanez L, Fernandez MV, Blennow K, Zetterberg H, Heslegrave A, Johansson PM, Svensson J, Nellgård B, Lleo A, Alcolea D, Clarimon J, Rami L, Molinuevo JL, Suárez-Calvet M, Morenas-Rodríguez E, Kleinberger G, Ewers M, Harari O, Haass C, Brett TJ, Benitez BA, Karch CM, Piccio L, Cruchaga C. Deming Y, et al. Sci Transl Med. 2019 Aug 14;11(505):eaau2291. doi: 10.1126/scitranslmed.aau2291. Sci Transl Med. 2019. PMID: 31413141 Free PMC article.
TREM2-Ligand Interactions in Health and Disease.
Kober DL, Brett TJ. Kober DL, et al. J Mol Biol. 2017 Jun 2;429(11):1607-1629. doi: 10.1016/j.jmb.2017.04.004. Epub 2017 Apr 19. J Mol Biol. 2017. PMID: 28432014 Free PMC article. Review.
Overlapping genetic architecture between Parkinson disease and melanoma.
Dube U, Ibanez L, Budde JP, Benitez BA, Davis AA, Harari O, Iles MM, Law MH, Brown KM; 23andMe Research Team; Melanoma-Meta-analysis Consortium; Cruchaga C. Dube U, et al. Acta Neuropathol. 2020 Feb;139(2):347-364. doi: 10.1007/s00401-019-02110-z. Epub 2019 Dec 16. Acta Neuropathol. 2020. PMID: 31845298 Free PMC article.
24 results