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Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping.
Yang H, Sui P, Guo Y, Chen S, Maloof ME, Ge G, Nihozeko F, Delma CR, Zhu G, Zhang P, Ye Z, Medina EA, Ayad NG, Mesa R, Nimer SD, Chiang CM, Xu M, Chen Y, Yang FC. Yang H, et al. EMBO Rep. 2023 Oct 9;24(10):e57032. doi: 10.15252/embr.202357032. Epub 2023 Aug 31. EMBO Rep. 2023. PMID: 37650863 Free article.
Context dependent effects of ascorbic acid treatment in TET2 mutant myeloid neoplasia.
Guan Y, Greenberg EF, Hasipek M, Chen S, Liu X, Kerr CM, Gackowski D, Zarakowska E, Radivoyevitch T, Gu X, Willard B, Visconte V, Makishima H, Nazha A, Mukherji M, Sekeres MA, Saunthararajah Y, Oliński R, Xu M, Maciejewski JP, Jha BK. Guan Y, et al. Commun Biol. 2020 Sep 7;3(1):493. doi: 10.1038/s42003-020-01220-9. Commun Biol. 2020. PMID: 32895473 Free PMC article.
IDH1/2 Mutations Sensitize Acute Myeloid Leukemia to PARP Inhibition and This Is Reversed by IDH1/2-Mutant Inhibitors.
Molenaar RJ, Radivoyevitch T, Nagata Y, Khurshed M, Przychodzen B, Makishima H, Xu M, Bleeker FE, Wilmink JW, Carraway HE, Mukherjee S, Sekeres MA, van Noorden CJF, Maciejewski JP. Molenaar RJ, et al. Clin Cancer Res. 2018 Apr 1;24(7):1705-1715. doi: 10.1158/1078-0432.CCR-17-2796. Epub 2018 Jan 16. Clin Cancer Res. 2018. PMID: 29339439 Free PMC article.