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Loss of BRD4 induces cell senescence in HSC/HPCs by deregulating histone H3 clipping.
Yang H, Sui P, Guo Y, Chen S, Maloof ME, Ge G, Nihozeko F, Delma CR, Zhu G, Zhang P, Ye Z, Medina EA, Ayad NG, Mesa R, Nimer SD, Chiang CM, Xu M, Chen Y, Yang FC. Yang H, et al. EMBO Rep. 2023 Oct 9;24(10):e57032. doi: 10.15252/embr.202357032. Epub 2023 Aug 31. EMBO Rep. 2023. PMID: 37650863 Free article.
INTS11 regulates hematopoiesis by promoting PRC2 function.
Zhang P, Sui P, Chen S, Guo Y, Li Y, Ge G, Zhu G, Yang H, Rogers CM, Sung P, Nimer SD, Xu M, Yang FC. Zhang P, et al. Sci Adv. 2021 Sep 3;7(36):eabh1684. doi: 10.1126/sciadv.abh1684. Epub 2021 Sep 1. Sci Adv. 2021. PMID: 34516911 Free PMC article.