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2022 4
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2024 2

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Page 1
Sitting leg vasculopathy: potential adaptations beyond the endothelium.
Ferreira-Santos L, Martinez-Lemus LA, Padilla J. Ferreira-Santos L, et al. Am J Physiol Heart Circ Physiol. 2024 Mar 1;326(3):H760-H771. doi: 10.1152/ajpheart.00489.2023. Epub 2024 Jan 19. Am J Physiol Heart Circ Physiol. 2024. PMID: 38241008 Review.
Neuraminidase-induced externalization of phosphatidylserine activates ADAM17 and impairs insulin signaling in endothelial cells.
Ferreira-Santos L, Ramirez-Perez FI, Foote CA, Augenreich MA, McMillan NJ, Williams MB, Gonzalez-Vallejo JD, Power G, Wheeler AA, Manrique-Acevedo C, Martinez-Lemus LA, Padilla J. Ferreira-Santos L, et al. Am J Physiol Heart Circ Physiol. 2024 Jan 1;326(1):H270-H277. doi: 10.1152/ajpheart.00638.2023. Epub 2023 Nov 24. Am J Physiol Heart Circ Physiol. 2024. PMID: 37999645
Impact of sex and diet-induced weight loss on vascular insulin sensitivity in type 2 diabetes.
Manrique-Acevedo C, Soares RN, Smith JA, Park LK, Burr K, Ramirez-Perez FI, McMillan NJ, Ferreira-Santos L, Sharma N, Olver TD, Emter CA, Parks EJ, Limberg JK, Martinez-Lemus LA, Padilla J. Manrique-Acevedo C, et al. Am J Physiol Regul Integr Comp Physiol. 2023 Mar 1;324(3):R293-R304. doi: 10.1152/ajpregu.00249.2022. Epub 2023 Jan 9. Am J Physiol Regul Integr Comp Physiol. 2023. PMID: 36622084 Free PMC article.
ADAM17 cleaves the insulin receptor ectodomain on endothelial cells and causes vascular insulin resistance.
Ghiarone T, Castorena-Gonzalez JA, Foote CA, Ramirez-Perez FI, Ferreira-Santos L, Cabral-Amador FJ, de la Torre R, Ganga RR, Wheeler AA, Manrique-Acevedo C, Padilla J, Martinez-Lemus LA. Ghiarone T, et al. Am J Physiol Heart Circ Physiol. 2022 Oct 1;323(4):H688-H701. doi: 10.1152/ajpheart.00039.2022. Epub 2022 Aug 26. Am J Physiol Heart Circ Physiol. 2022. PMID: 36018759 Free PMC article.
Endothelial HSP72 is not reduced in type 2 diabetes nor is it a key determinant of endothelial insulin sensitivity.
Pettit-Mee RJ, Power G, Cabral-Amador FJ, Ramirez-Perez FI, Soares RN, Sharma N, Liu Y, Christou DD, Kanaley JA, Martinez-Lemus LA, Manrique-Acevedo C, Padilla J. Pettit-Mee RJ, et al. Am J Physiol Regul Integr Comp Physiol. 2022 Jul 1;323(1):R43-R58. doi: 10.1152/ajpregu.00006.2022. Epub 2022 Apr 26. Am J Physiol Regul Integr Comp Physiol. 2022. PMID: 35470695 Free PMC article.