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Huntington's disease alters human neurodevelopment.
Barnat M, Capizzi M, Aparicio E, Boluda S, Wennagel D, Kacher R, Kassem R, Lenoir S, Agasse F, Braz BY, Liu JP, Ighil J, Tessier A, Zeitlin SO, Duyckaerts C, Dommergues M, Durr A, Humbert S. Barnat M, et al. Science. 2020 Aug 14;369(6505):787-793. doi: 10.1126/science.aax3338. Epub 2020 Jul 16. Science. 2020. PMID: 32675289 Free PMC article.
Is Huntingtin Dispensable in the Adult Brain?
Liu JP, Zeitlin SO. Liu JP, et al. J Huntingtons Dis. 2017;6(1):1-17. doi: 10.3233/JHD-170235. J Huntingtons Dis. 2017. PMID: 28339401 Free PMC article. Review.
Benefits of global mutant huntingtin lowering diminish over time in a Huntington's disease mouse model.
Marchionini DM, Liu JP, Ambesi-Impiombato A, Kerker K, Cirillo K, Bansal M, Mushlin R, Brunner D, Ramboz S, Kwan M, Kuhlbrodt K, Tillack K, Peters F, Rauhala L, Obenauer J, Greene JR, Hartl C, Khetarpal V, Lager B, Rosinski J, Aaronson J, Alam M, Signer E, Muñoz-Sanjuán I, Howland D, Zeitlin SO. Marchionini DM, et al. JCI Insight. 2022 Oct 24;7(20):e161769. doi: 10.1172/jci.insight.161769. JCI Insight. 2022. PMID: 36278490 Free PMC article.