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Azure C Targets and Modulates Toxic Tau Oligomers.
Lo Cascio F, Kayed R. Lo Cascio F, et al. ACS Chem Neurosci. 2018 Jun 20;9(6):1317-1326. doi: 10.1021/acschemneuro.7b00501. Epub 2018 Mar 1. ACS Chem Neurosci. 2018. PMID: 29378132
α-Synuclein Oligomers Induce a Unique Toxic Tau Strain.
Castillo-Carranza DL, Guerrero-Muñoz MJ, Sengupta U, Gerson JE, Kayed R. Castillo-Carranza DL, et al. Biol Psychiatry. 2018 Oct 1;84(7):499-508. doi: 10.1016/j.biopsych.2017.12.018. Epub 2018 Jan 17. Biol Psychiatry. 2018. PMID: 29478699 Free PMC article.
Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.
Nguyen PH, Ramamoorthy A, Sahoo BR, Zheng J, Faller P, Straub JE, Dominguez L, Shea JE, Dokholyan NV, De Simone A, Ma B, Nussinov R, Najafi S, Ngo ST, Loquet A, Chiricotto M, Ganguly P, McCarty J, Li MS, Hall C, Wang Y, Miller Y, Melchionna S, Habenstein B, Timr S, Chen J, Hnath B, Strodel B, Kayed R, Lesné S, Wei G, Sterpone F, Doig AJ, Derreumaux P. Nguyen PH, et al. Chem Rev. 2021 Feb 24;121(4):2545-2647. doi: 10.1021/acs.chemrev.0c01122. Epub 2021 Feb 5. Chem Rev. 2021. PMID: 33543942 Free PMC article. Review.
Modulating disease-relevant tau oligomeric strains by small molecules.
Lo Cascio F, Garcia S, Montalbano M, Puangmalai N, McAllen S, Pace A, Palumbo Piccionello A, Kayed R. Lo Cascio F, et al. J Biol Chem. 2020 Oct 30;295(44):14807-14825. doi: 10.1074/jbc.RA120.014630. Epub 2020 Jul 31. J Biol Chem. 2020. PMID: 32737202 Free PMC article.
24 results