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2018 4
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2023 9
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Page 1
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells.
Lee J, Robinson ME, Ma N, Artadji D, Ahmed MA, Xiao G, Sadras T, Deb G, Winchester J, Cosgun KN, Geng H, Chan LN, Kume K, Miettinen TP, Zhang Y, Nix MA, Klemm L, Chen CW, Chen J, Khairnar V, Wiita AP, Thomas-Tikhonenko A, Farzan M, Jung JU, Weinstock DM, Manalis SR, Diamond MS, Vaidehi N, Müschen M. Lee J, et al. Nature. 2020 Dec;588(7838):491-497. doi: 10.1038/s41586-020-2884-6. Epub 2020 Nov 4. Nature. 2020. PMID: 33149299 Free PMC article.
Molecular annotation of G protein variants in a neurological disorder.
Knight KM, Obarow EG, Wei W, Mani S, Esteller MI, Cui M, Ma N, Martin SA, Brinson E, Hewitt N, Soden GM, Logothetis DE, Vaidehi N, Dohlman HG. Knight KM, et al. Cell Rep. 2023 Dec 26;42(12):113462. doi: 10.1016/j.celrep.2023.113462. Epub 2023 Nov 18. Cell Rep. 2023. PMID: 37980565 Free PMC article.
A universal allosteric mechanism for G protein activation.
Knight KM, Ghosh S, Campbell SL, Lefevre TJ, Olsen RHJ, Smrcka AV, Valentin NH, Yin G, Vaidehi N, Dohlman HG. Knight KM, et al. Mol Cell. 2021 Apr 1;81(7):1384-1396.e6. doi: 10.1016/j.molcel.2021.02.002. Epub 2021 Feb 25. Mol Cell. 2021. PMID: 33636126 Free PMC article.
How Do Branched Detergents Stabilize GPCRs in Micelles?
Lee S, Ghosh S, Jana S, Robertson N, Tate CG, Vaidehi N. Lee S, et al. Biochemistry. 2020 Jun 16;59(23):2125-2134. doi: 10.1021/acs.biochem.0c00183. Epub 2020 Jun 5. Biochemistry. 2020. PMID: 32437610 Free PMC article.
Catalytic site mutations confer multiple states of G protein activation.
Hewitt N, Ma N, Arang N, Martin SA, Prakash A, DiBerto JF, Knight KM, Ghosh S, Olsen RHJ, Roth BL, Gutkind JS, Vaidehi N, Campbell SL, Dohlman HG. Hewitt N, et al. Sci Signal. 2023 Feb 14;16(772):eabq7842. doi: 10.1126/scisignal.abq7842. Epub 2023 Feb 14. Sci Signal. 2023. PMID: 36787384 Free PMC article.
30 results