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PTPN22: the archetypal non-HLA autoimmunity gene.
Stanford SM, Bottini N. Stanford SM, et al. Nat Rev Rheumatol. 2014 Oct;10(10):602-11. doi: 10.1038/nrrheum.2014.109. Epub 2014 Jul 8. Nat Rev Rheumatol. 2014. PMID: 25003765 Free PMC article. Review.
The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity.
Wang Y, Shaked I, Stanford SM, Zhou W, Curtsinger JM, Mikulski Z, Shaheen ZR, Cheng G, Sawatzke K, Campbell AM, Auger JL, Bilgic H, Shoyama FM, Schmeling DO, Balfour HH Jr, Hasegawa K, Chan AC, Corbett JA, Binstadt BA, Mescher MF, Ley K, Bottini N, Peterson EJ. Wang Y, et al. Immunity. 2013 Jul 25;39(1):111-22. doi: 10.1016/j.immuni.2013.06.013. Epub 2013 Jul 18. Immunity. 2013. PMID: 23871208 Free PMC article.
Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.
Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM, Wu DJ, Hsieh YW, Maine CJ, Christensen M, Kuchroo V, Sherman LA, Podolin PL, Todd JA, Steward CA, Peterson LB, Bottini N, Wicker LS. Fraser HI, et al. J Immunol. 2015 Nov 15;195(10):4841-52. doi: 10.4049/jimmunol.1402654. Epub 2015 Oct 5. J Immunol. 2015. PMID: 26438525 Free PMC article.