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Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).
Kielczewski JL, Li Calzi S, Shaw LC, Cai J, Qi X, Ruan Q, Wu L, Liu L, Hu P, Chan-Ling T, Mames RN, Firth S, Baxter RC, Turowski P, Busik JV, Boulton ME, Grant MB. Kielczewski JL, et al. Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8278-86. doi: 10.1167/iovs.11-8167. Invest Ophthalmol Vis Sci. 2011. PMID: 21931131 Free PMC article.