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Page 1
The carboxy-terminus, a key regulator of protein function.
Sharma S, Schiller MR. Sharma S, et al. Crit Rev Biochem Mol Biol. 2019 Apr;54(2):85-102. doi: 10.1080/10409238.2019.1586828. Epub 2019 May 20. Crit Rev Biochem Mol Biol. 2019. PMID: 31106589 Free PMC article. Review.
The Functional Human C-Terminome.
Sharma S, Toledo O, Hedden M, Lyon KF, Brooks SB, David RP, Limtong J, Newsome JM, Novakovic N, Rajasekaran S, Thapar V, Williams SR, Schiller MR. Sharma S, et al. PLoS One. 2016 Apr 6;11(4):e0152731. doi: 10.1371/journal.pone.0152731. eCollection 2016. PLoS One. 2016. PMID: 27050421 Free PMC article.
Minimotif Miner 4: a million peptide minimotifs and counting.
Lyon KF, Cai X, Young RJ, Mamun AA, Rajasekaran S, Schiller MR. Lyon KF, et al. Nucleic Acids Res. 2018 Jan 4;46(D1):D465-D470. doi: 10.1093/nar/gkx1085. Nucleic Acids Res. 2018. PMID: 29140456 Free PMC article.
Novel algorithms for LDD motif search.
Xiao P, Schiller M, Rajasekaran S. Xiao P, et al. BMC Genomics. 2019 Jun 6;20(Suppl 5):424. doi: 10.1186/s12864-019-5701-6. BMC Genomics. 2019. PMID: 31167665 Free PMC article.
Minimotifs dysfunction is pervasive in neurodegenerative disorders.
Sharma S, Young RJ, Chen J, Chen X, Oh EC, Schiller MR. Sharma S, et al. Alzheimers Dement (N Y). 2018 Jul 25;4:414-432. doi: 10.1016/j.trci.2018.06.005. eCollection 2018. Alzheimers Dement (N Y). 2018. PMID: 30225339 Free PMC article.
GigaAssay - An adaptable high-throughput saturation mutagenesis assay platform.
Benjamin R, Giacoletto CJ, FitzHugh ZT, Eames D, Buczek L, Wu X, Newsome J, Han MV, Pearson T, Wei Z, Banerjee A, Brown L, Valente LJ, Shen S, Deng HW, Schiller MR. Benjamin R, et al. Genomics. 2022 Jul;114(4):110439. doi: 10.1016/j.ygeno.2022.110439. Epub 2022 Jul 26. Genomics. 2022. PMID: 35905834 Free PMC article.