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Ornithine decarboxylase, the rate-limiting enzyme of polyamine synthesis, modifies brain pathology in a mouse model of tuberous sclerosis complex.
Hum Mol Genet. 2020 Aug 11;29(14):2395-2407. doi: 10.1093/hmg/ddaa121.
Hum Mol Genet. 2020.
PMID: 32588887
Free PMC article.
Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex.
McKenna J 3rd, Kapfhamer D, Kinchen JM, Wasek B, Dunworth M, Murray-Stewart T, Bottiglieri T, Casero RA Jr, Gambello MJ.
McKenna J 3rd, et al.
Hum Mol Genet. 2018 Jun 15;27(12):2113-2124. doi: 10.1093/hmg/ddy118.
Hum Mol Genet. 2018.
PMID: 29635516
Free PMC article.
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