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Accelerated DNA methylation age: Associations with PTSD and neural integrity.
Wolf EJ, Logue MW, Hayes JP, Sadeh N, Schichman SA, Stone A, Salat DH, Milberg W, McGlinchey R, Miller MW. Wolf EJ, et al. Psychoneuroendocrinology. 2016 Jan;63:155-62. doi: 10.1016/j.psyneuen.2015.09.020. Epub 2015 Sep 30. Psychoneuroendocrinology. 2016. PMID: 26447678 Free PMC article.
SKA2 methylation is associated with decreased prefrontal cortical thickness and greater PTSD severity among trauma-exposed veterans.
Sadeh N, Spielberg JM, Logue MW, Wolf EJ, Smith AK, Lusk J, Hayes JP, Sperbeck E, Milberg WP, McGlinchey RE, Salat DH, Carter WC, Stone A, Schichman SA, Humphries DE, Miller MW. Sadeh N, et al. Mol Psychiatry. 2016 Mar;21(3):357-63. doi: 10.1038/mp.2015.134. Epub 2015 Sep 1. Mol Psychiatry. 2016. PMID: 26324104 Free PMC article.
A novel locus in the oxidative stress-related gene ALOX12 moderates the association between PTSD and thickness of the prefrontal cortex.
Miller MW, Wolf EJ, Sadeh N, Logue M, Spielberg JM, Hayes JP, Sperbeck E, Schichman SA, Stone A, Carter WC, Humphries DE, Milberg W, McGlinchey R. Miller MW, et al. Psychoneuroendocrinology. 2015 Dec;62:359-65. doi: 10.1016/j.psyneuen.2015.09.003. Epub 2015 Sep 5. Psychoneuroendocrinology. 2015. PMID: 26372769 Free PMC article.
An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress.
Logue MW, Smith AK, Baldwin C, Wolf EJ, Guffanti G, Ratanatharathorn A, Stone A, Schichman SA, Humphries D, Binder EB, Arloth J, Menke A, Uddin M, Wildman D, Galea S, Aiello AE, Koenen KC, Miller MW. Logue MW, et al. Psychoneuroendocrinology. 2015 Jul;57:1-13. doi: 10.1016/j.psyneuen.2015.03.016. Epub 2015 Mar 24. Psychoneuroendocrinology. 2015. PMID: 25867994 Free PMC article.