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Year Number of Results
2020 2
2021 8
2022 2
2023 2
2024 0

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14 results

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Page 1
tRNA dysregulation and disease.
Orellana EA, Siegal E, Gregory RI. Orellana EA, et al. Nat Rev Genet. 2022 Nov;23(11):651-664. doi: 10.1038/s41576-022-00501-9. Epub 2022 Jun 9. Nat Rev Genet. 2022. PMID: 35681060 Review.
METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation.
Orellana EA, Liu Q, Yankova E, Pirouz M, De Braekeleer E, Zhang W, Lim J, Aspris D, Sendinc E, Garyfallos DA, Gu M, Ali R, Gutierrez A, Mikutis S, Bernardes GJL, Fischer ES, Bradley A, Vassiliou GS, Slack FJ, Tzelepis K, Gregory RI. Orellana EA, et al. Mol Cell. 2021 Aug 19;81(16):3323-3338.e14. doi: 10.1016/j.molcel.2021.06.031. Epub 2021 Aug 4. Mol Cell. 2021. PMID: 34352207 Free PMC article.
Structural basis of regulated m7G tRNA modification by METTL1-WDR4.
Li J, Wang L, Hahn Q, Nowak RP, Viennet T, Orellana EA, Roy Burman SS, Yue H, Hunkeler M, Fontana P, Wu H, Arthanari H, Fischer ES, Gregory RI. Li J, et al. Nature. 2023 Jan;613(7943):391-397. doi: 10.1038/s41586-022-05566-4. Epub 2023 Jan 4. Nature. 2023. PMID: 36599985
Exon junction complex shapes the m6A epitranscriptome.
Yang X, Triboulet R, Liu Q, Sendinc E, Gregory RI. Yang X, et al. Nat Commun. 2022 Dec 23;13(1):7904. doi: 10.1038/s41467-022-35643-1. Nat Commun. 2022. PMID: 36550132 Free PMC article.
Mining for METTL3 inhibitors to suppress cancer.
Li J, Gregory RI. Li J, et al. Nat Struct Mol Biol. 2021 Jun;28(6):460-462. doi: 10.1038/s41594-021-00606-5. Nat Struct Mol Biol. 2021. PMID: 34040230 Free PMC article.
LIN28B alters ribosomal dynamics to promote metastasis in MYCN-driven malignancy.
Missios P, da Rocha EL, Pearson DS, Philipp J, Aleman MM, Pirouz M, Farache D, Franses JW, Kubaczka C, Tsanov KM, Jha DK, Pepe-Mooney B, Powers JT, Gregory RI, Lee AS, Dominguez D, Ting DT, Daley GQ. Missios P, et al. J Clin Invest. 2021 Nov 15;131(22):e145142. doi: 10.1172/JCI145142. J Clin Invest. 2021. PMID: 34779407 Free PMC article.
14 results