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Cryo-EM structure of a RAS/RAF recruitment complex.
Park E, Rawson S, Schmoker A, Kim BW, Oh S, Song K, Jeon H, Eck MJ. Park E, et al. Nat Commun. 2023 Jul 29;14(1):4580. doi: 10.1038/s41467-023-40299-6. Nat Commun. 2023. PMID: 37516774 Free PMC article.
The structural basis of PTEN regulation by multi-site phosphorylation.
Dempsey DR, Viennet T, Iwase R, Park E, Henriquez S, Chen Z, Jeliazkov JR, Palanski BA, Phan KL, Coote P, Gray JJ, Eck MJ, Gabelli SB, Arthanari H, Cole PA. Dempsey DR, et al. Nat Struct Mol Biol. 2021 Oct;28(10):858-868. doi: 10.1038/s41594-021-00668-5. Epub 2021 Oct 8. Nat Struct Mol Biol. 2021. PMID: 34625746 Free PMC article.
Structural Basis for Inhibition of Mutant EGFR with Lazertinib (YH25448).
Heppner DE, Wittlinger F, Beyett TS, Shaurova T, Urul DA, Buckley B, Pham CD, Schaeffner IK, Yang B, Ogboo BC, May EW, Schaefer EM, Eck MJ, Laufer SA, Hershberger PA. Heppner DE, et al. ACS Med Chem Lett. 2022 Nov 10;13(12):1856-1863. doi: 10.1021/acsmedchemlett.2c00213. eCollection 2022 Dec 8. ACS Med Chem Lett. 2022. PMID: 36518696 Free PMC article.
17 results