R35 GM122542/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2017	1
2018	2
2019	4
2020	1
2021	5
2022	7
2023	1
2024	0

1

Drugging the efferocytosis process: concepts and opportunities.

Mehrotra P, Ravichandran KS. Mehrotra P, et al. Nat Rev Drug Discov. 2022 Aug;21(8):601-620. doi: 10.1038/s41573-022-00470-y. Epub 2022 Jun 1. Nat Rev Drug Discov. 2022. PMID: 35650427 Free PMC article. Review.

2

Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes.

Maschalidi S, Mehrotra P, Keçeli BN, De Cleene HKL, Lecomte K, Van der Cruyssen R, Janssen P, Pinney J, van Loo G, Elewaut D, Massie A, Hoste E, Ravichandran KS. Maschalidi S, et al. Nature. 2022 Jun;606(7915):776-784. doi: 10.1038/s41586-022-04754-6. Epub 2022 May 25. Nature. 2022. PMID: 35614212

3

Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity.

Wiernicki B, Maschalidi S, Pinney J, Adjemian S, Vanden Berghe T, Ravichandran KS, Vandenabeele P. Wiernicki B, et al. Nat Commun. 2022 Jun 27;13(1):3676. doi: 10.1038/s41467-022-31218-2. Nat Commun. 2022. PMID: 35760796 Free PMC article.

4

Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation.

Morioka S, Kajioka D, Yamaoka Y, Ellison RM, Tufan T, Werkman IL, Tanaka S, Barron B, Ito ST, Kucenas S, Okusa MD, Ravichandran KS. Morioka S, et al. Cell. 2022 Dec 22;185(26):4887-4903.e17. doi: 10.1016/j.cell.2022.11.029. Cell. 2022. PMID: 36563662 Free PMC article.

5

Metabolites released from apoptotic cells act as tissue messengers.

Medina CB, Mehrotra P, Arandjelovic S, Perry JSA, Guo Y, Morioka S, Barron B, Walk SF, Ghesquière B, Krupnick AS, Lorenz U, Ravichandran KS. Medina CB, et al. Nature. 2020 Apr;580(7801):130-135. doi: 10.1038/s41586-020-2121-3. Epub 2020 Mar 18. Nature. 2020. PMID: 32238926 Free PMC article.

6

Live cell tracking of macrophage efferocytosis during Drosophila embryo development in vivo.

Raymond MH, Davidson AJ, Shen Y, Tudor DR, Lucas CD, Morioka S, Perry JSA, Krapivkina J, Perrais D, Schumacher LJ, Campbell RE, Wood W, Ravichandran KS. Raymond MH, et al. Science. 2022 Mar 11;375(6585):1182-1187. doi: 10.1126/science.abl4430. Epub 2022 Mar 10. Science. 2022. PMID: 35271315 Free PMC article.

7

Living on the Edge: Efferocytosis at the Interface of Homeostasis and Pathology.

Morioka S, Maueröder C, Ravichandran KS. Morioka S, et al. Immunity. 2019 May 21;50(5):1149-1162. doi: 10.1016/j.immuni.2019.04.018. Immunity. 2019. PMID: 31117011 Free PMC article. Review.

8

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.

Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS. Morioka S, et al. Nature. 2018 Nov;563(7733):714-718. doi: 10.1038/s41586-018-0735-5. Epub 2018 Nov 21. Nature. 2018. PMID: 30464343 Free PMC article.

9

Phagocytosis in the retina promotes local insulin production in the eye.

Iker Etchegaray J, Kelley S, Penberthy K, Karvelyte L, Nagasaka Y, Gasperino S, Paul S, Seshadri V, Raymond M, Marco AR, Pinney J, Stremska M, Barron B, Lucas C, Wase N, Fan Y, Unanue E, Kundu B, Burstyn-Cohen T, Perry J, Ambati J, Ravichandran KS. Iker Etchegaray J, et al. Nat Metab. 2023 Feb;5(2):207-218. doi: 10.1038/s42255-022-00728-0. Epub 2023 Feb 2. Nat Metab. 2023. PMID: 36732622 Free PMC article.

10

Microbes exploit death-induced nutrient release by gut epithelial cells.

Anderson CJ, Medina CB, Barron BJ, Karvelyte L, Aaes TL, Lambertz I, Perry JSA, Mehrotra P, Gonçalves A, Lemeire K, Blancke G, Andries V, Ghazavi F, Martens A, van Loo G, Vereecke L, Vandenabeele P, Ravichandran KS. Anderson CJ, et al. Nature. 2021 Aug;596(7871):262-267. doi: 10.1038/s41586-021-03785-9. Epub 2021 Aug 4. Nature. 2021. PMID: 34349263

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