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HIV Type 1 Nef is released from infected cells in CD45(+) microvesicles and is present in the plasma of HIV-infected individuals.
AIDS Res Hum Retroviruses. 2011 Feb;27(2):167-78. doi: 10.1089/aid.2009.0170. Epub 2010 Oct 21.
AIDS Res Hum Retroviruses. 2011.
PMID: 20964480
Free PMC article.
Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.
Ehrlich LS, Medina GN, Khan MB, Powell MD, Mikoshiba K, Carter CA.
Ehrlich LS, et al.
J Virol. 2010 Jul;84(13):6438-51. doi: 10.1128/JVI.01588-09. Epub 2010 Apr 28.
J Virol. 2010.
PMID: 20427533
Free PMC article.
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HIV-1 Nef protein is secreted into vesicles that can fuse with target cells and virions.
Campbell TD, Khan M, Huang MB, Bond VC, Powell MD.
Campbell TD, et al.
Ethn Dis. 2008 Spring;18(2 Suppl 2):S2-14-9.
Ethn Dis. 2008.
PMID: 18646314
Free PMC article.
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