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R(+)XK469 inhibits hydroxylation of S-warfarin by CYP2C9.
Yong WP, Kim TW, Undevia SD, Innocenti F, Ratain MJ. Yong WP, et al. Eur J Cancer. 2009 Jul;45(11):1904-8. doi: 10.1016/j.ejca.2009.04.032. Epub 2009 May 21. Eur J Cancer. 2009. PMID: 19464879 Free PMC article.
Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity.
Rudin CM, Liu W, Desai A, Karrison T, Jiang X, Janisch L, Das S, Ramirez J, Poonkuzhali B, Schuetz E, Fackenthal DL, Chen P, Armstrong DK, Brahmer JR, Fleming GF, Vokes EE, Carducci MA, Ratain MJ. Rudin CM, et al. J Clin Oncol. 2008 Mar 1;26(7):1119-27. doi: 10.1200/JCO.2007.13.1128. J Clin Oncol. 2008. PMID: 18309947 Free PMC article.
A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
Ramírez J, Kim TW, Liu W, Myers JL, Mirkov S, Owzar K, Watson D, Mulkey F, Gamazon ER, Stock W, Undevia S, Innocenti F, Ratain MJ. Ramírez J, et al. Pharmacogenet Genomics. 2014 Feb;24(2):129-32. doi: 10.1097/FPC.0000000000000023. Pharmacogenet Genomics. 2014. PMID: 24300566 Free PMC article.
A phase I and pharmacodynamic study of the histone deacetylase inhibitor belinostat plus azacitidine in advanced myeloid neoplasia.
Odenike O, Halpern A, Godley LA, Madzo J, Karrison T, Green M, Fulton N, Mattison RJ, Yee KW, Bennett M, Koval G, Malnassy G, Larson RA, Ratain MJ, Stock W. Odenike O, et al. Invest New Drugs. 2015 Apr;33(2):371-9. doi: 10.1007/s10637-014-0194-2. Epub 2014 Dec 9. Invest New Drugs. 2015. PMID: 25483416 Free PMC article. Clinical Trial.