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Evidence for age as a modifier of genetic associations for lipid levels.
Dumitrescu L, Brown-Gentry K, Goodloe R, Glenn K, Yang W, Kornegay N, Pui CH, Relling MV, Crawford DC. Dumitrescu L, et al. Ann Hum Genet. 2011 Sep;75(5):589-97. doi: 10.1111/j.1469-1809.2011.00664.x. Epub 2011 Jul 21. Ann Hum Genet. 2011. PMID: 21777205 Free PMC article.
Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia.
Yang JJ, Cheng C, Devidas M, Cao X, Fan Y, Campana D, Yang W, Neale G, Cox NJ, Scheet P, Borowitz MJ, Winick NJ, Martin PL, Willman CL, Bowman WP, Camitta BM, Carroll A, Reaman GH, Carroll WL, Loh M, Hunger SP, Pui CH, Evans WE, Relling MV. Yang JJ, et al. Nat Genet. 2011 Mar;43(3):237-41. doi: 10.1038/ng.763. Epub 2011 Feb 6. Nat Genet. 2011. PMID: 21297632 Free PMC article.
Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis.
Meyer zu Schwabedissen HE, Ware JA, Finkelstein D, Chaudhry AS, Mansell S, Leon-Ponte M, Strom SC, Zaher H, Schwarz UI, Freeman DJ, Schuetz EG, Tirona RG, Kim RB. Meyer zu Schwabedissen HE, et al. Hepatology. 2011 Aug;54(2):644-54. doi: 10.1002/hep.24391. Epub 2011 Jun 26. Hepatology. 2011. PMID: 21538436 Free PMC article.
Functional characterization of liver enhancers that regulate drug-associated transporters.
Kim MJ, Skewes-Cox P, Fukushima H, Hesselson S, Yee SW, Ramsey LB, Nguyen L, Eshragh JL, Castro RA, Wen CC, Stryke D, Johns SJ, Ferrin TE, Kwok PY, Relling MV, Giacomini KM, Kroetz DL, Ahituv N. Kim MJ, et al. Clin Pharmacol Ther. 2011 Apr;89(4):571-8. doi: 10.1038/clpt.2010.353. Epub 2011 Mar 2. Clin Pharmacol Ther. 2011. PMID: 21368754 Free PMC article.