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Opposing effects on regulated insulin secretion of acute vs chronic stimulation of AMP-activated protein kinase.
Nguyen-Tu MS, Harris J, Martinez-Sanchez A, Chabosseau P, Hu M, Georgiadou E, Pollard A, Otero P, Lopez-Noriega L, Leclerc I, Sakamoto K, Schmoll D, Smith DM, Carling D, Rutter GA. Nguyen-Tu MS, et al. Diabetologia. 2022 Jun;65(6):997-1011. doi: 10.1007/s00125-022-05673-x. Epub 2022 Mar 16. Diabetologia. 2022. PMID: 35294578 Free PMC article.
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.
Yu V, Yong F, Marta A, Khadayate S, Osakwe A, Bhattacharya S, Varghese SS, Chabosseau P, Tabibi SM, Chen K, Georgiadou E, Parveen N, Suleiman M, Stamoulis Z, Marselli L, De Luca C, Tesi M, Ostinelli G, Delgadillo-Silva L, Wu X, Hatanaka Y, Montoya A, Elliott J, Patel B, Demchenko N, Whilding C, Hajkova P, Shliaha P, Kramer H, Ali Y, Marchetti P, Sladek R, Dhawan S, Withers DJ, Rutter GA, Millership SJ. Yu V, et al. Diabetologia. 2024 Jun;67(6):1079-1094. doi: 10.1007/s00125-024-06123-6. Epub 2024 Mar 21. Diabetologia. 2024. PMID: 38512414 Free PMC article.
Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.
Mousavy Gharavy SN, Owen BM, Millership SJ, Chabosseau P, Pizza G, Martinez-Sanchez A, Tasoez E, Georgiadou E, Hu M, Fine NHF, Jacobson DA, Dickerson MT, Idevall-Hagren O, Montoya A, Kramer H, Mehta Z, Withers DJ, Ninov N, Gadue PJ, Cardenas-Diaz FL, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Leclerc I, Voz M, Rutter GA. Mousavy Gharavy SN, et al. Diabetologia. 2021 Apr;64(4):850-864. doi: 10.1007/s00125-020-05350-x. Epub 2021 Jan 25. Diabetologia. 2021. PMID: 33492421 Free PMC article.
Glucose in the hypothalamic paraventricular nucleus regulates GLP-1 release.
Ma Y, Ratnasabapathy R, De Backer I, Izzi-Engbeaya C, Nguyen-Tu MS, Cuenco J, Jones B, John CD, Lam BY, Rutter GA, Yeo GS, Dhillo WS, Gardiner J. Ma Y, et al. JCI Insight. 2020 Mar 31;5(8):e132760. doi: 10.1172/jci.insight.132760. JCI Insight. 2020. PMID: 32229720 Free PMC article.