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Page 1
The human intestinal cytochrome P450 "pie".
Paine MF, Hart HL, Ludington SS, Haining RL, Rettie AE, Zeldin DC. Paine MF, et al. Drug Metab Dispos. 2006 May;34(5):880-6. doi: 10.1124/dmd.105.008672. Epub 2006 Feb 7. Drug Metab Dispos. 2006. PMID: 16467132 Free PMC article.
CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime].
Wang MZ, Saulter JY, Usuki E, Cheung YL, Hall M, Bridges AS, Loewen G, Parkinson OT, Stephens CE, Allen JL, Zeldin DC, Boykin DW, Tidwell RR, Parkinson A, Paine MF, Hall JE. Wang MZ, et al. Drug Metab Dispos. 2006 Dec;34(12):1985-94. doi: 10.1124/dmd.106.010587. Epub 2006 Sep 22. Drug Metab Dispos. 2006. PMID: 16997912 Free PMC article.
Cytochrome P-450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-alpha via MAPK and PI3K/Akt signaling pathways.
Yang S, Lin L, Chen JX, Lee CR, Seubert JM, Wang Y, Wang H, Chao ZR, Tao DD, Gong JP, Lu ZY, Wang DW, Zeldin DC. Yang S, et al. Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H142-51. doi: 10.1152/ajpheart.00783.2006. Epub 2007 Feb 23. Am J Physiol Heart Circ Physiol. 2007. PMID: 17322420 Free PMC article.
16 results