ZIA BC010816/ImNIH/Intramural NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2016	2
2019	2
2020	4
2022	1
2023	3
2024	0

1

Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results.

Hassan R, Butler M, O'Cearbhaill RE, Oh DY, Johnson M, Zikaras K, Smalley M, Ross M, Tanyi JL, Ghafoor A, Shah NN, Saboury B, Cao L, Quintás-Cardama A, Hong D. Hassan R, et al. Nat Med. 2023 Aug;29(8):2099-2109. doi: 10.1038/s41591-023-02452-y. Epub 2023 Jul 27. Nat Med. 2023. PMID: 37501016 Free PMC article. Clinical Trial.

2

Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma.

Nair NU, Jiang Q, Wei JS, Misra VA, Morrow B, Kesserwan C, Hermida LC, Lee JS, Mian I, Zhang J, Lebensohn A, Miettinen M, Sengupta M, Khan J, Ruppin E, Hassan R. Nair NU, et al. Cell Rep Med. 2023 Feb 21;4(2):100938. doi: 10.1016/j.xcrm.2023.100938. Epub 2023 Feb 10. Cell Rep Med. 2023. PMID: 36773602 Free PMC article.

3

Orbital metastases from malignant mesothelioma.

Mian I, Padiernos E, Hassan R, Ghafoor A. Mian I, et al. Lancet Oncol. 2020 Feb;21(2):e117. doi: 10.1016/S1470-2045(19)30822-8. Lancet Oncol. 2020. PMID: 32007197 Free PMC article. No abstract available.

4

NAV-003, a bispecific antibody targeting a unique mesothelin epitope and CD3ε with improved cytotoxicity against humoral immunosuppressed tumors.

Grasso L, Jiang Q, Hassan R, Nicolaides NC, Kline JB. Grasso L, et al. Eur J Immunol. 2023 Aug;53(8):e2250309. doi: 10.1002/eji.202250309. Epub 2023 Jun 20. Eur J Immunol. 2023. PMID: 37146241

5

Response to Letter to Editor by Cornelissen et al.

Hassan R, Miettinen M. Hassan R, et al. J Thorac Oncol. 2020 Oct;15(10):e169-e170. doi: 10.1016/j.jtho.2020.07.003. J Thorac Oncol. 2020. PMID: 32981607 Free PMC article. No abstract available.

6

Expression of mesothelin in thymic carcinoma and its potential therapeutic significance.

Thomas A, Chen Y, Berman A, Schrump DS, Giaccone G, Pastan I, Venzon DJ, Liewehr DJ, Steinberg SM, Miettinen M, Hassan R, Rajan A. Thomas A, et al. Lung Cancer. 2016 Nov;101:104-110. doi: 10.1016/j.lungcan.2016.09.015. Epub 2016 Sep 28. Lung Cancer. 2016. PMID: 27794397 Free PMC article.

7

Clinical Response of Live-Attenuated, Listeria monocytogenes Expressing Mesothelin (CRS-207) with Chemotherapy in Patients with Malignant Pleural Mesothelioma.

Hassan R, Alley E, Kindler H, Antonia S, Jahan T, Honarmand S, Nair N, Whiting CC, Enstrom A, Lemmens E, Tsujikawa T, Kumar S, Choe G, Thomas A, McDougall K, Murphy AL, Jaffee E, Coussens LM, Brockstedt DG. Hassan R, et al. Clin Cancer Res. 2019 Oct 1;25(19):5787-5798. doi: 10.1158/1078-0432.CCR-19-0070. Epub 2019 Jul 1. Clin Cancer Res. 2019. PMID: 31263030 Free PMC article. Clinical Trial.

8

Development of Highly Effective Anti-Mesothelin hYP218 Chimeric Antigen Receptor T Cells With Increased Tumor Infiltration and Persistence for Treating Solid Tumors.

Tomar S, Zhang J, Khanal M, Hong J, Venugopalan A, Jiang Q, Sengupta M, Miettinen M, Li N, Pastan I, Ho M, Hassan R. Tomar S, et al. Mol Cancer Ther. 2022 Jul 5;21(7):1195-1206. doi: 10.1158/1535-7163.MCT-22-0073. Mol Cancer Ther. 2022. PMID: 35499461 Free PMC article.

9

Enhanced efficacy of mesothelin-targeted immunotoxin LMB-100 and anti-PD-1 antibody in patients with mesothelioma and mouse tumor models.

Jiang Q, Ghafoor A, Mian I, Rathkey D, Thomas A, Alewine C, Sengupta M, Ahlman MA, Zhang J, Morrow B, Steinberg SM, Pastan I, Hassan R. Jiang Q, et al. Sci Transl Med. 2020 Jul 1;12(550):eaaz7252. doi: 10.1126/scitranslmed.aaz7252. Sci Transl Med. 2020. PMID: 32611684 Free PMC article.

10

CD70 expression correlates with a worse prognosis in malignant pleural mesothelioma patients via immune evasion and enhanced invasiveness.

Inaguma S, Lasota J, Czapiewski P, Langfort R, Rys J, Szpor J, Waloszczyk P, Okoń K, Biernat W, Schrump DS, Hassan R, Kasai K, Miettinen M, Ikeda H. Inaguma S, et al. J Pathol. 2020 Feb;250(2):205-216. doi: 10.1002/path.5361. Epub 2019 Dec 3. J Pathol. 2020. PMID: 31639216 Free PMC article.

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