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Year | Number of Results |
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2019 | 1 |
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Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases.
J Nat Prod. 2023 Oct 27;86(10):2283-2293. doi: 10.1021/acs.jnatprod.3c00394. Epub 2023 Oct 16.
J Nat Prod. 2023.
PMID: 37843072
Free PMC article.
Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines.
Cai S, Risinger AL, Petersen CL, Grkovic T, O'Keefe BR, Mooberry SL, Cichewicz RH.
Cai S, et al.
J Nat Prod. 2019 Apr 26;82(4):928-936. doi: 10.1021/acs.jnatprod.8b01015. Epub 2019 Mar 4.
J Nat Prod. 2019.
PMID: 30830773
Free PMC article.
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Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1).
Bermingham A, Price E, Marchand C, Chergui A, Naumova A, Whitson EL, Krumpe LRH, Goncharova EI, Evans JR, McKee TC, Henrich CJ, Pommier Y, O'Keefe BR.
Bermingham A, et al.
SLAS Discov. 2017 Oct;22(9):1093-1105. doi: 10.1177/2472555217717200. Epub 2017 Jul 11.
SLAS Discov. 2017.
PMID: 28697309
Free PMC article.
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Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I.
Krumpe LRH, Wilson BAP, Marchand C, Sunassee SN, Bermingham A, Wang W, Price E, Guszczynski T, Kelley JA, Gustafson KR, Pommier Y, Rosengren KJ, Schroeder CI, O'Keefe BR.
Krumpe LRH, et al.
J Am Chem Soc. 2020 Dec 16;142(50):21178-21188. doi: 10.1021/jacs.0c10418. Epub 2020 Dec 2.
J Am Chem Soc. 2020.
PMID: 33263997
Free PMC article.
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