092809/Wellcome Trust/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2011	7
2012	19
2013	31
2014	84
2015	11
2024	0

1

Open access chemical probes for epigenetic targets.

Brown PJ, Müller S. Brown PJ, et al. Future Med Chem. 2015;7(14):1901-17. doi: 10.4155/fmc.15.127. Epub 2015 Sep 23. Future Med Chem. 2015. PMID: 26397018 Free PMC article. Review.

2

Bisubstrate inhibitor approach for targeting mitotic kinase Haspin.

Kestav K, Lavogina D, Raidaru G, Chaikuad A, Knapp S, Uri A. Kestav K, et al. Bioconjug Chem. 2015 Feb 18;26(2):225-34. doi: 10.1021/bc500464r. Epub 2015 Jan 29. Bioconjug Chem. 2015. PMID: 25595038

3

Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.

Perfetti MT, Baughman BM, Dickson BM, Mu Y, Cui G, Mader P, Dong A, Norris JL, Rothbart SB, Strahl BD, Brown PJ, Janzen WP, Arrowsmith CH, Mer G, McBride KM, James LI, Frye SV. Perfetti MT, et al. ACS Chem Biol. 2015 Apr 17;10(4):1072-81. doi: 10.1021/cb500956g. Epub 2015 Jan 28. ACS Chem Biol. 2015. PMID: 25590533 Free PMC article.

4

Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis.

Van Rechem C, Black JC, Boukhali M, Aryee MJ, Gräslund S, Haas W, Benes CH, Whetstine JR. Van Rechem C, et al. Cancer Discov. 2015 Mar;5(3):255-63. doi: 10.1158/2159-8290.CD-14-1326. Epub 2015 Jan 6. Cancer Discov. 2015. PMID: 25564516 Free PMC article.

5

Structure-activity relationship studies of SETD8 inhibitors.

Ma A, Yu W, Xiong Y, Butler KV, Brown PJ, Jin J. Ma A, et al. Medchemcomm. 2014 Dec;5(12):1892-1898. doi: 10.1039/C4MD00317A. Medchemcomm. 2014. PMID: 25554733 Free PMC article.

6

Purification and interaction analyses of two human lysosomal vitamin B12 transporters: LMBD1 and ABCD4.

Deme JC, Hancock MA, Xia X, Shintre CA, Plesa M, Kim JC, Carpenter EP, Rosenblatt DS, Coulton JW. Deme JC, et al. Mol Membr Biol. 2014 Nov-Dec;31(7-8):250-61. doi: 10.3109/09687688.2014.990998. Mol Membr Biol. 2014. PMID: 25535791

7

Recombinant renewable polyclonal antibodies.

Ferrara F, D'Angelo S, Gaiotto T, Naranjo L, Tian H, Gräslund S, Dobrovetsky E, Hraber P, Lund-Johansen F, Saragozza S, Sblattero D, Kiss C, Bradbury AR. Ferrara F, et al. MAbs. 2015;7(1):32-41. doi: 10.4161/19420862.2015.989047. MAbs. 2015. PMID: 25530082 Free PMC article.

8

Crystal Structure of Sphingosine Kinase 1 with PF-543.

Wang J, Knapp S, Pyne NJ, Pyne S, Elkins JM. Wang J, et al. ACS Med Chem Lett. 2014 Oct 27;5(12):1329-33. doi: 10.1021/ml5004074. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25516793 Free PMC article.

9

BAZ2A (TIP5) is involved in epigenetic alterations in prostate cancer and its overexpression predicts disease recurrence.

Gu L, Frommel SC, Oakes CC, Simon R, Grupp K, Gerig CY, Bär D, Robinson MD, Baer C, Weiss M, Gu Z, Schapira M, Kuner R, Sültmann H, Provenzano M; ICGC Project on Early Onset Prostate Cancer; Yaspo ML, Brors B, Korbel J, Schlomm T, Sauter G, Eils R, Plass C, Santoro R. Gu L, et al. Nat Genet. 2015 Jan;47(1):22-30. doi: 10.1038/ng.3165. Epub 2014 Dec 8. Nat Genet. 2015. PMID: 25485837

10

Structure and function of dioxygenases in histone demethylation and DNA/RNA demethylation.

Dong C, Zhang H, Xu C, Arrowsmith CH, Min J. Dong C, et al. IUCrJ. 2014 Oct 28;1(Pt 6):540-9. doi: 10.1107/S2052252514020922. eCollection 2014 Nov 1. IUCrJ. 2014. PMID: 25485134 Free PMC article. Review.

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