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Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent.
Hübel C, Gaspar HA, Coleman JRI, Hanscombe KB, Purves K, Prokopenko I, Graff M, Ngwa JS, Workalemahu T; ADHD Working Group of the Psychiatric Genomics Consortium; Meta-Analyses of Glucose and Insulin-related traits consortium (MAGIC); Autism Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium; PTSD Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Sex Differences Cross Disorder Working Group of the Psychiatric Genomics Consortium; Substance Use Disorders Working Group of the Psychiatric Genomics Consortium; German Borderline Genomics Consortium; International Headache Genetics Consortium; O'Reilly PF, Bulik CM, Breen G. Hübel C, et al. Nat Commun. 2019 Dec 18;10(1):5765. doi: 10.1038/s41467-019-13544-0. Nat Commun. 2019. PMID: 31852892 Free PMC article.
Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.
Hübel C, Gaspar HA, Coleman JRI, Finucane H, Purves KL, Hanscombe KB, Prokopenko I; MAGIC investigators; Graff M, Ngwa JS, Workalemahu T; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Tourette Syndrome/Obsessive-Compulsive Disorder Working Group of the Psychiatric Genomics Consortium; O'Reilly PF, Bulik CM, Breen G. Hübel C, et al. Am J Med Genet B Neuropsychiatr Genet. 2019 Sep;180(6):428-438. doi: 10.1002/ajmg.b.32709. Epub 2018 Dec 28. Am J Med Genet B Neuropsychiatr Genet. 2019. PMID: 30593698 Free PMC article.