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The liquid-to-solid transition of FUS is promoted by the condensate surface.
Shen Y, Chen A, Wang W, Shen Y, Ruggeri FS, Aime S, Wang Z, Qamar S, Espinosa JR, Garaizar A, St George-Hyslop P, Collepardo-Guevara R, Weitz DA, Vigolo D, Knowles TPJ. Shen Y, et al. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2301366120. doi: 10.1073/pnas.2301366120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549257 Free PMC article.
Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.
Arter WE, Qi R, Erkamp NA, Krainer G, Didi K, Welsh TJ, Acker J, Nixon-Abell J, Qamar S, Guillén-Boixet J, Franzmann TM, Kuster D, Hyman AA, Borodavka A, George-Hyslop PS, Alberti S, Knowles TPJ. Arter WE, et al. Nat Commun. 2022 Dec 21;13(1):7845. doi: 10.1038/s41467-022-35265-7. Nat Commun. 2022. PMID: 36543777 Free PMC article.
Decreased Water Mobility Contributes To Increased α-Synuclein Aggregation.
Stephens AD, Kölbel J, Moons R, Chung CW, Ruggiero MT, Mahmoudi N, Shmool TA, McCoy TM, Nietlispach D, Routh AF, Sobott F, Zeitler JA, Kaminski Schierle GS. Stephens AD, et al. Angew Chem Int Ed Engl. 2023 Feb 6;62(7):e202212063. doi: 10.1002/anie.202212063. Epub 2023 Jan 12. Angew Chem Int Ed Engl. 2023. PMID: 36316279 Free PMC article.
101 results