20771/ARC_/Arthritis Research UK/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2016	6
2017	4
2018	2
2019	3
2024	0

1

Expression analysis of the osteoarthritis genetic susceptibility mapping to the matrix Gla protein gene MGP.

Shepherd C, Reese AE, Reynard LN, Loughlin J. Shepherd C, et al. Arthritis Res Ther. 2019 Jun 18;21(1):149. doi: 10.1186/s13075-019-1934-7. Arthritis Res Ther. 2019. PMID: 31215457 Free PMC article.

2

Functional testing of thousands of osteoarthritis-associated variants for regulatory activity.

Klein JC, Keith A, Rice SJ, Shepherd C, Agarwal V, Loughlin J, Shendure J. Klein JC, et al. Nat Commun. 2019 Jun 4;10(1):2434. doi: 10.1038/s41467-019-10439-y. Nat Commun. 2019. PMID: 31164647 Free PMC article.

3

Prioritization of PLEC and GRINA as Osteoarthritis Risk Genes Through the Identification and Characterization of Novel Methylation Quantitative Trait Loci.

Rice SJ, Tselepi M, Sorial AK, Aubourg G, Shepherd C, Almarza D, Skelton AJ, Pangou I, Deehan D, Reynard LN, Loughlin J. Rice SJ, et al. Arthritis Rheumatol. 2019 Aug;71(8):1285-1296. doi: 10.1002/art.40849. Epub 2019 Jun 27. Arthritis Rheumatol. 2019. PMID: 30730609 Free PMC article.

4

Identification of a novel, methylation-dependent, RUNX2 regulatory region associated with osteoarthritis risk.

Rice SJ, Aubourg G, Sorial AK, Almarza D, Tselepi M, Deehan DJ, Reynard LN, Loughlin J. Rice SJ, et al. Hum Mol Genet. 2018 Oct 1;27(19):3464-3474. doi: 10.1093/hmg/ddy257. Hum Mol Genet. 2018. PMID: 30010910 Free PMC article.

5

Functional Characterization of the Osteoarthritis Genetic Risk Residing at ALDH1A2 Identifies rs12915901 as a Key Target Variant.

Shepherd C, Zhu D, Skelton AJ, Combe J, Threadgold H, Zhu L, Vincent TL, Stuart P, Reynard LN, Loughlin J. Shepherd C, et al. Arthritis Rheumatol. 2018 Oct;70(10):1577-1587. doi: 10.1002/art.40545. Epub 2018 Aug 23. Arthritis Rheumatol. 2018. PMID: 29732726 Free PMC article.

6

Genome editing for human osteoarthritis - a perspective.

Almarza D, Cucchiarini M, Loughlin J. Almarza D, et al. Osteoarthritis Cartilage. 2017 Aug;25(8):1195-1198. doi: 10.1016/j.joca.2017.05.003. Epub 2017 May 18. Osteoarthritis Cartilage. 2017. PMID: 28529161 Free article. No abstract available.

7

A consistent and potentially exploitable response during chondrogenesis of mesenchymal stem cells from osteoarthritis patients to the protein encoded by the susceptibility gene GDF5.

Ratnayake M, Tselepi M, Bloxham R, Plöger F, Reynard LN, Loughlin J. Ratnayake M, et al. PLoS One. 2017 May 8;12(5):e0176523. doi: 10.1371/journal.pone.0176523. eCollection 2017. PLoS One. 2017. PMID: 28481944 Free PMC article.

8

Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis.

Styrkarsdottir U, Helgason H, Sigurdsson A, Norddahl GL, Agustsdottir AB, Reynard LN, Villalvilla A, Halldorsson GH, Jonasdottir A, Magnusdottir A, Oddson A, Sulem G, Zink F, Sveinbjornsson G, Helgason A, Johannsdottir HS, Helgadottir A, Stefansson H, Gretarsdottir S, Rafnar T, Almdahl IS, Brækhus A, Fladby T, Selbæk G, Hosseinpanah F, Azizi F, Koh JM, Tang NLS, Daneshpour MS, Mayordomo JI, Welt C, Braund PS, Samani NJ, Kiemeney LA, Lohmander LS, Christiansen C, Andreassen OA; arcOGEN consortium; Magnusson O, Masson G, Kong A, Jonsdottir I, Gudbjartsson D, Sulem P, Jonsson H, Loughlin J, Ingvarsson T, Thorsteinsdottir U, Stefansson K. Styrkarsdottir U, et al. Nat Genet. 2017 May;49(5):801-805. doi: 10.1038/ng.3816. Epub 2017 Mar 20. Nat Genet. 2017. PMID: 28319091

9

A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells.

Peffers MJ, Collins J, Loughlin J, Proctor C, Clegg PD. Peffers MJ, et al. Stem Cell Res Ther. 2016 Sep 14;7(1):133. doi: 10.1186/s13287-016-0384-2. Stem Cell Res Ther. 2016. PMID: 27624072 Free PMC article.

10

Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq.

Peffers MJ, Goljanek-Whysall K, Collins J, Fang Y, Rushton M, Loughlin J, Proctor C, Clegg PD. Peffers MJ, et al. PLoS One. 2016 Aug 17;11(8):e0160517. doi: 10.1371/journal.pone.0160517. eCollection 2016. PLoS One. 2016. PMID: 27533049 Free PMC article.

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