Abad MC - Search Results

Year	Number of Results
2002	4
2005	2
2006	2
2007	3
2008	4
2009	1
2010	2
2011	4
2024	0

1

Electron density guided fragment-based drug design--a lead generation example.

Abad MC, Gibbs AC, Zhang X. Abad MC, et al. Methods Enzymol. 2011;493:487-508. doi: 10.1016/B978-0-12-381274-2.00019-4. Methods Enzymol. 2011. PMID: 21371603

2

Potency variation of small-molecule chymase inhibitors across species.

Kervinen J, Crysler C, Bayoumy S, Abad MC, Spurlino J, Deckman I, Greco MN, Maryanoff BE, de Garavilla L. Kervinen J, et al. Among authors: abad mc. Biochem Pharmacol. 2010 Oct 1;80(7):1033-41. doi: 10.1016/j.bcp.2010.06.014. Epub 2010 Jun 23. Biochem Pharmacol. 2010. PMID: 20599788

3

Optimization of a pyrazole hit from FBDD into a novel series of indazoles as ketohexokinase inhibitors.

Zhang X, Song F, Kuo GH, Xiang A, Gibbs AC, Abad MC, Sun W, Kuo LC, Sui Z. Zhang X, et al. Among authors: abad mc. Bioorg Med Chem Lett. 2011 Aug 15;21(16):4762-7. doi: 10.1016/j.bmcl.2011.06.067. Epub 2011 Jun 29. Bioorg Med Chem Lett. 2011. PMID: 21767952

4

The X-ray crystallographic structure of Escherichia coli branching enzyme.

Abad MC, Binderup K, Rios-Steiner J, Arni RK, Preiss J, Geiger JH. Abad MC, et al. J Biol Chem. 2002 Nov 1;277(44):42164-70. doi: 10.1074/jbc.M205746200. Epub 2002 Aug 23. J Biol Chem. 2002. PMID: 12196524 Free article.

5

Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site.

Maryanoff BE, O'Neill JC, McComsey DF, Yabut SC, Luci DK, Jordan AD Jr, Masucci JA, Jones WJ, Abad MC, Gibbs AC, Petrounia I. Maryanoff BE, et al. Among authors: abad mc. ACS Med Chem Lett. 2011 Apr 18;2(7):538-43. doi: 10.1021/ml200070g. eCollection 2011 Jul 14. ACS Med Chem Lett. 2011. PMID: 24900346 Free PMC article.

6

Novel tetrahydroisoquinolines are histamine H3 antagonists and serotonin reuptake inhibitors.

Letavic MA, Keith JM, Jablonowski JA, Stocking EM, Gomez LA, Ly KS, Miller JM, Barbier AJ, Bonaventure P, Boggs JD, Wilson SJ, Miller KL, Lord B, McAllister HM, Tognarelli DJ, Wu J, Abad MC, Schubert C, Lovenberg TW, Carruthers NI. Letavic MA, et al. Among authors: abad mc. Bioorg Med Chem Lett. 2007 Feb 15;17(4):1047-51. doi: 10.1016/j.bmcl.2006.11.036. Epub 2006 Nov 16. Bioorg Med Chem Lett. 2007. PMID: 17127059

7

Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents.

Patch RJ, Searle LL, Kim AJ, De D, Zhu X, Askari HB, O'Neill JC, Abad MC, Rentzeperis D, Liu J, Kemmerer M, Lin L, Kasturi J, Geisler JG, Lenhard JM, Player MR, Gaul MD. Patch RJ, et al. Among authors: abad mc. J Med Chem. 2011 Feb 10;54(3):788-808. doi: 10.1021/jm101063h. Epub 2011 Jan 10. J Med Chem. 2011. PMID: 21218783

8

Improved strategies for the delivery of GFP-based Ca2+ sensors into the mitochondrial matrix.

Filippin L, Abad MC, Gastaldello S, Magalhães PJ, Sandonà D, Pozzan T. Filippin L, et al. Among authors: abad mc. Cell Calcium. 2005 Feb;37(2):129-36. doi: 10.1016/j.ceca.2004.08.002. Cell Calcium. 2005. PMID: 15589993

9

4-Amino-6-arylamino-pyrimidine-5-carbaldehyde hydrazones as potent ErbB-2/EGFR dual kinase inhibitors.

Xu G, Abad MC, Connolly PJ, Neeper MP, Struble GT, Springer BA, Emanuel SL, Pandey N, Gruninger RH, Adams M, Moreno-Mazza S, Fuentes-Pesquera AR, Middleton SA. Xu G, et al. Among authors: abad mc. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4615-9. doi: 10.1016/j.bmcl.2008.07.020. Epub 2008 Jul 10. Bioorg Med Chem Lett. 2008. PMID: 18653333

10

Electron density guided fragment-based lead discovery of ketohexokinase inhibitors.

Gibbs AC, Abad MC, Zhang X, Tounge BA, Lewandowski FA, Struble GT, Sun W, Sui Z, Kuo LC. Gibbs AC, et al. Among authors: abad mc. J Med Chem. 2010 Nov 25;53(22):7979-91. doi: 10.1021/jm100677s. Epub 2010 Oct 29. J Med Chem. 2010. PMID: 21033679

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