Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer's disease.
Gonzalez-Ortiz F, Kirsebom BE, Contador J, Tanley JE, Selnes P, Gísladóttir B, Pålhaugen L, Suhr Hemminghyth M, Jarholm J, Skogseth R, Bråthen G, Grøndtvedt G, Bjørnerud A, Tecelao S, Waterloo K, Aarsland D, Fernández-Lebrero A, García-Escobar G, Navalpotro-Gómez I, Turton M, Hesthamar A, Kac PR, Nilsson J, Luchsinger J, Hayden KM, Harrison P, Puig-Pijoan A, Zetterberg H, Hughes TM, Suárez-Calvet M, Karikari TK, Fladby T, Blennow K.
Gonzalez-Ortiz F, et al.
Nat Commun. 2024 Apr 4;15(1):2908. doi: 10.1038/s41467-024-47286-5.
Nat Commun. 2024.
PMID: 38575616
Free PMC article.
In blood, phosphorylated tau (p-tau) associates with Abeta pathophysiology but an AD-type neurodegeneration biomarker has been lacking. ...Here we show that blood-based BD-tau is a biomarker for identifying Abeta-positive individuals at risk of short-term cognitive …
In blood, phosphorylated tau (p-tau) associates with Abeta pathophysiology but an AD-type neurodegeneration biomarker has been lackin …