Abramov AY - Search Results

1

Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function.

Esteras N, Dinkova-Kostova AT, Abramov AY. Esteras N, et al. Among authors: abramov ay. Biol Chem. 2016 May;397(5):383-400. doi: 10.1515/hsz-2015-0295. Biol Chem. 2016. PMID: 26812787 Free article. Review.

2

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration.

Holmström KM, Baird L, Zhang Y, Hargreaves I, Chalasani A, Land JM, Stanyer L, Yamamoto M, Dinkova-Kostova AT, Abramov AY. Holmström KM, et al. Among authors: abramov ay. Biol Open. 2013 Jun 20;2(8):761-70. doi: 10.1242/bio.20134853. eCollection 2013 Aug 15. Biol Open. 2013. PMID: 23951401 Free PMC article.

3

Nrf2 affects the efficiency of mitochondrial fatty acid oxidation.

Ludtmann MH, Angelova PR, Zhang Y, Abramov AY, Dinkova-Kostova AT. Ludtmann MH, et al. Among authors: abramov ay. Biochem J. 2014 Feb 1;457(3):415-24. doi: 10.1042/BJ20130863. Biochem J. 2014. PMID: 24206218 Free PMC article.

4

Nrf2 regulates ROS production by mitochondria and NADPH oxidase.

Kovac S, Angelova PR, Holmström KM, Zhang Y, Dinkova-Kostova AT, Abramov AY. Kovac S, et al. Among authors: abramov ay. Biochim Biophys Acta. 2015 Apr;1850(4):794-801. doi: 10.1016/j.bbagen.2014.11.021. Epub 2014 Dec 5. Biochim Biophys Acta. 2015. PMID: 25484314 Free PMC article.

5

The emerging role of Nrf2 in mitochondrial function.

Dinkova-Kostova AT, Abramov AY. Dinkova-Kostova AT, et al. Among authors: abramov ay. Free Radic Biol Med. 2015 Nov;88(Pt B):179-188. doi: 10.1016/j.freeradbiomed.2015.04.036. Epub 2015 May 11. Free Radic Biol Med. 2015. PMID: 25975984 Free PMC article. Review.

6

The spatiotemporal regulation of the Keap1-Nrf2 pathway and its importance in cellular bioenergetics.

Dinkova-Kostova AT, Baird L, Holmström KM, Meyer CJ, Abramov AY. Dinkova-Kostova AT, et al. Among authors: abramov ay. Biochem Soc Trans. 2015 Aug;43(4):602-10. doi: 10.1042/BST20150003. Epub 2015 Aug 3. Biochem Soc Trans. 2015. PMID: 26551700 Free PMC article.

7

Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation.

Delgado-Camprubi M, Esteras N, Soutar MP, Plun-Favreau H, Abramov AY. Delgado-Camprubi M, et al. Among authors: abramov ay. Cell Death Differ. 2017 Jan;24(1):120-131. doi: 10.1038/cdd.2016.104. Epub 2016 Sep 30. Cell Death Differ. 2017. PMID: 27689878 Free PMC article.

8

Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration.

Esteras N, Rohrer JD, Hardy J, Wray S, Abramov AY. Esteras N, et al. Among authors: abramov ay. Redox Biol. 2017 Aug;12:410-422. doi: 10.1016/j.redox.2017.03.008. Epub 2017 Mar 10. Redox Biol. 2017. PMID: 28319892 Free PMC article.

9

Pathogenic p62/SQSTM1 mutations impair energy metabolism through limitation of mitochondrial substrates.

Bartolome F, Esteras N, Martin-Requero A, Boutoleau-Bretonniere C, Vercelletto M, Gabelle A, Le Ber I, Honda T, Dinkova-Kostova AT, Hardy J, Carro E, Abramov AY. Bartolome F, et al. Among authors: abramov ay. Sci Rep. 2017 May 10;7(1):1666. doi: 10.1038/s41598-017-01678-4. Sci Rep. 2017. PMID: 28490746 Free PMC article.

10

Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation.

Delgado-Camprubi M, Esteras N, Soutar MP, Plun-Favreau H, Abramov AY. Delgado-Camprubi M, et al. Among authors: abramov ay. Cell Death Differ. 2017 Dec;24(12):2210. doi: 10.1038/cdd.2017.175. Epub 2017 Oct 13. Cell Death Differ. 2017. PMID: 29027992 Free PMC article.

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