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The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis.
bioRxiv [Preprint]. 2023 Apr 8:2023.04.07.536026. doi: 10.1101/2023.04.07.536026.
bioRxiv. 2023.
PMID: 37066336
Free PMC article.
Preprint.
Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium.
Dunlap G, Wagner A, Meednu N, Zhang F, Jonsson AH, Wei K, Sakaue S, Nathan A; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Bykerk VP, Donlin LT, Goodman SM, Firestein GS, Boyle DL, Holers VM, Moreland LW, Tabechian D, Pitzalis C, Filer A, Raychaudhuri S, Brenner MB, McDavid A, Rao DA, Anolik JH.
Dunlap G, et al.
bioRxiv [Preprint]. 2023 Mar 21:2023.03.18.533282. doi: 10.1101/2023.03.18.533282.
bioRxiv. 2023.
PMID: 36993527
Free PMC article.
Preprint.
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Adipocytes regulate fibroblast function, and their loss contributes to fibroblast dysfunction in inflammatory diseases.
Faust HJ, Cheng TY, Korsunsky I, Watts GFM, Gal-Oz ST, Trim W, Kongthong K, Jonsson AH, Simmons DP, Zhang F, Padera R, Chubinskaya S; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Wei K, Raychaudhuri S, Lynch L, Moody DB, Brenner MB.
Faust HJ, et al.
bioRxiv [Preprint]. 2023 May 18:2023.05.16.540975. doi: 10.1101/2023.05.16.540975.
bioRxiv. 2023.
PMID: 37292637
Free PMC article.
Preprint.
We performed RNA sequencing of healthy human synovial tissue and identified a fibroblast gene expression program characterized by enhanced fatty acid metabolism and lipid transport. ...
We performed RNA sequencing of healthy human synovial tissue and identified a fibroblast gene expression program characterized by enh …
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Machine Learning Reveals Synovial Fibroblast Genes Associated with Pain Affect Sensory Nerve Growth in Rheumatoid Arthritis.
Bai Z, Bartelo N, Aslam M, Hale C, Blachere NE, Parveen S, Spolaore E, DiCarlo E, Gravallese E, Smith MH; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Frank MO, Jiang CS, Zhang H, Lewis MJ, Sikandar S, Pitzalis C, Malfait AM, Miller RE, Zhang F, Goodman S, Darnell R, Wang F, Orange DE.
Bai Z, et al.
medRxiv [Preprint]. 2023 Aug 23:2023.08.17.23294232. doi: 10.1101/2023.08.17.23294232.
medRxiv. 2023.
PMID: 37662384
Free PMC article.
Preprint.
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Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
Kang JB, Shen AZ, Sakaue S, Luo Y, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta K, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, Dey K; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Daly MJ, Xavier RJ, Donlin LT, Anolik JH, Powell JE, Rao DA, Brenner MB, Gutierrez-Arcelus M, Raychaudhuri S.
Kang JB, et al.
medRxiv [Preprint]. 2023 Mar 20:2023.03.14.23287257. doi: 10.1101/2023.03.14.23287257.
medRxiv. 2023.
PMID: 36993194
Free PMC article.
Updated.
Preprint.
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Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
Kang JB, Shen AZ, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta KA, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, Dey K; Accelerating Medicines Partnership Program: Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Network; Daly MJ, Xavier RJ, Donlin LT, Anolik JH, Powell JE, Rao DA, Brenner MB, Gutierrez-Arcelus M, Luo Y, Sakaue S, Raychaudhuri S.
Kang JB, et al.
Nat Genet. 2023 Dec;55(12):2255-2268. doi: 10.1038/s41588-023-01586-6. Epub 2023 Nov 30.
Nat Genet. 2023.
PMID: 38036787
Free PMC article.
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