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A method and server for predicting damaging missense mutations.
Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. Adzhubei IA, et al. Nat Methods. 2010 Apr;7(4):248-9. doi: 10.1038/nmeth0410-248. Nat Methods. 2010. PMID: 20354512 Free PMC article. No abstract available.
Human mutation rate associated with DNA replication timing.
Stamatoyannopoulos JA, Adzhubei I, Thurman RE, Kryukov GV, Mirkin SM, Sunyaev SR. Stamatoyannopoulos JA, et al. Nat Genet. 2009 Apr;41(4):393-5. doi: 10.1038/ng.363. Epub 2009 Mar 15. Nat Genet. 2009. PMID: 19287383 Free PMC article.
A universal trend of amino acid gain and loss in protein evolution.
Jordan IK, Kondrashov FA, Adzhubei IA, Wolf YI, Koonin EV, Kondrashov AS, Sunyaev S. Jordan IK, et al. Among authors: adzhubei ia. Nature. 2005 Feb 10;433(7026):633-8. doi: 10.1038/nature03306. Epub 2005 Jan 19. Nature. 2005. PMID: 15660107
Erratum.
Schmidt S, Gerasimova A, Kondrashov FA, Adzhubei IA, Kondrashov AS, Sunyaev S. Schmidt S, et al. Among authors: adzhubei ia. PLoS Genet. 2008 Dec;4(12):10.1371/annotation/a81b1fab-890c-447b-a308-5bc8ca3eb21d. doi: 10.1371/annotation/a81b1fab-890c-447b-a308-5bc8ca3eb21d. Epub 2008 Dec 10. PLoS Genet. 2008. PMID: 19096535 Free PMC article.
Hypermutable non-synonymous sites are under stronger negative selection.
Schmidt S, Gerasimova A, Kondrashov FA, Adzhubei IA, Adzuhbei IA, Kondrashov AS, Sunyaev S. Schmidt S, et al. Among authors: adzhubei ia. PLoS Genet. 2008 Nov;4(11):e1000281. doi: 10.1371/journal.pgen.1000281. Epub 2008 Nov 28. PLoS Genet. 2008. PMID: 19043566 Free PMC article.
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
ENCODE Project Consortium; Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foiss… See abstract for full author list ➔ ENCODE Project Consortium, et al. Nature. 2007 Jun 14;447(7146):799-816. doi: 10.1038/nature05874. Nature. 2007. PMID: 17571346 Free PMC article.
28 results