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A missense mutation in LRR8 of RXFP2 is associated with cryptorchidism.
Harris RM, Finlayson C, Weiss J, Fisher L, Hurley L, Barrett T, Emge D, Bathgate RA, Agoulnik AI, Jameson JL. Harris RM, et al. Among authors: agoulnik ai. Mamm Genome. 2010 Oct;21(9-10):442-9. doi: 10.1007/s00335-010-9291-5. Epub 2010 Oct 22. Mamm Genome. 2010. PMID: 20963592
INSL3/RXFP2 signaling in testicular descent.
Feng S, Ferlin A, Truong A, Bathgate R, Wade JD, Corbett S, Han S, Tannour-Louet M, Lamb DJ, Foresta C, Agoulnik AI. Feng S, et al. Among authors: agoulnik ai. Ann N Y Acad Sci. 2009 Apr;1160:197-204. doi: 10.1111/j.1749-6632.2009.03841.x. Ann N Y Acad Sci. 2009. PMID: 19416188 Free PMC article. Review.
ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.
Kocan M, Sarwar M, Ang SY, Xiao J, Marugan JJ, Hossain MA, Wang C, Hutchinson DS, Samuel CS, Agoulnik AI, Bathgate RAD, Summers RJ. Kocan M, et al. Among authors: agoulnik ai. Sci Rep. 2017 Jun 7;7(1):2968. doi: 10.1038/s41598-017-02916-5. Sci Rep. 2017. PMID: 28592882 Free PMC article.
Novel mutations involving the INSL3 gene associated with cryptorchidism.
El Houate B, Rouba H, Sibai H, Barakat A, Chafik A, Chadli el B, Imken L, Bogatcheva NV, Feng S, Agoulnik AI, McElreavey K. El Houate B, et al. Among authors: agoulnik ai. J Urol. 2007 May;177(5):1947-51. doi: 10.1016/j.juro.2007.01.002. J Urol. 2007. PMID: 17437853
Activation of Relaxin Family Receptor 1 from Different Mammalian Species by Relaxin Peptide and Small-Molecule Agonist ML290.
Huang Z, Myhr C, Bathgate RA, Ho BA, Bueno A, Hu X, Xiao J, Southall N, Barnaeva E, Agoulnik IU, Marugan JJ, Ferrer M, Agoulnik AI. Huang Z, et al. Among authors: agoulnik ai, agoulnik iu. Front Endocrinol (Lausanne). 2015 Aug 17;6:128. doi: 10.3389/fendo.2015.00128. eCollection 2015. Front Endocrinol (Lausanne). 2015. PMID: 26347712 Free PMC article.
A transgenic insertion causing cryptorchidism in mice.
Overbeek PA, Gorlov IP, Sutherland RW, Houston JB, Harrison WR, Boettger-Tong HL, Bishop CE, Agoulnik AI. Overbeek PA, et al. Among authors: agoulnik ai. Genesis. 2001 May;30(1):26-35. doi: 10.1002/gene.1029. Genesis. 2001. PMID: 11353515
Mutations of the GREAT gene cause cryptorchidism.
Gorlov IP, Kamat A, Bogatcheva NV, Jones E, Lamb DJ, Truong A, Bishop CE, McElreavey K, Agoulnik AI. Gorlov IP, et al. Among authors: agoulnik ai. Hum Mol Genet. 2002 Sep 15;11(19):2309-18. doi: 10.1093/hmg/11.19.2309. Hum Mol Genet. 2002. PMID: 12217959
T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane.
Bogatcheva NV, Ferlin A, Feng S, Truong A, Gianesello L, Foresta C, Agoulnik AI. Bogatcheva NV, et al. Among authors: agoulnik ai. Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E138-44. doi: 10.1152/ajpendo.00228.2006. Epub 2006 Aug 22. Am J Physiol Endocrinol Metab. 2007. PMID: 16926383 Free article.
88 results