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Regulation of Transforming Growth Factor β-Activated Kinase Activation by Epigallocatechin-3-Gallate in Rheumatoid Arthritis Synovial Fibroblasts: Suppression of K(63) -Linked Autoubiquitination of Tumor Necrosis Factor Receptor-Associated Factor 6.
Singh AK, Umar S, Riegsecker S, Chourasia M, Ahmed S. Singh AK, et al. Among authors: ahmed s. Arthritis Rheumatol. 2016 Feb;68(2):347-58. doi: 10.1002/art.39447. Arthritis Rheumatol. 2016. PMID: 26473505 Free PMC article.
Ursolic acid facilitates apoptosis in rheumatoid arthritis synovial fibroblasts by inducing SP1-mediated Noxa expression and proteasomal degradation of Mcl-1.
Kim EY, Sudini K, Singh AK, Haque M, Leaman D, Khuder S, Ahmed S. Kim EY, et al. Among authors: ahmed s. FASEB J. 2018 May 25;32(11):fj201800425R. doi: 10.1096/fj.201800425R. Online ahead of print. FASEB J. 2018. PMID: 29799788 Free PMC article.
-Kim, E. Y., Sudini, K., Singh, A. K., Haque, M., Leaman, D., Khuder, S., Ahmed, S. Ursolic acid facilitates apoptosis in rheumatoid arthritis synovial fibroblasts by inducing SP1-mediated Noxa expression and proteasomal degradation of Mcl-1....
-Kim, E. Y., Sudini, K., Singh, A. K., Haque, M., Leaman, D., Khuder, S., Ahmed, S. Ursolic acid facilitates apoptosis …
Critical role of IL-1α in IL-1β-induced inflammatory responses: cooperation with NF-κBp65 in transcriptional regulation.
Singh AK, Fechtner S, Chourasia M, Sicalo J, Ahmed S. Singh AK, et al. Among authors: ahmed s. FASEB J. 2019 Feb;33(2):2526-2536. doi: 10.1096/fj.201801513R. Epub 2018 Oct 1. FASEB J. 2019. PMID: 30272996 Free PMC article.
Our study highlights the importance of IL-1alpha in mediating IL-1beta-induced inflammation in addition to maintaining its expression and providing a rationale for targeting IL-1alpha to minimize the role of IL-1beta in inflammatory diseases like RA.-Singh, A. K., Fechtner, S
Our study highlights the importance of IL-1alpha in mediating IL-1beta-induced inflammation in addition to maintaining its expression and pr …
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