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The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenmüller W, Latz E. Franklin BS, et al. Nat Immunol. 2014 Aug;15(8):727-37. doi: 10.1038/ni.2913. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952505 Free PMC article.
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.
Alecu I, Tedeschi A, Behler N, Wunderling K, Lamberz C, Lauterbach MA, Gaebler A, Ernst D, Van Veldhoven PP, Al-Amoudi A, Latz E, Othman A, Kuerschner L, Hornemann T, Bradke F, Thiele C, Penno A. Alecu I, et al. J Lipid Res. 2017 Jan;58(1):42-59. doi: 10.1194/jlr.M068676. Epub 2016 Nov 23. J Lipid Res. 2017. PMID: 27881717 Free PMC article.
Structural studies on desmosomes.
Al-Amoudi A, Frangakis AS. Al-Amoudi A, et al. Biochem Soc Trans. 2008 Apr;36(Pt 2):181-7. doi: 10.1042/BST0360181. Biochem Soc Trans. 2008. PMID: 18363559 Review.
The three-dimensional molecular structure of the desmosomal plaque.
Al-Amoudi A, Castaño-Diez D, Devos DP, Russell RB, Johnson GT, Frangakis AS. Al-Amoudi A, et al. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6480-5. doi: 10.1073/pnas.1019469108. Epub 2011 Apr 4. Proc Natl Acad Sci U S A. 2011. PMID: 21464301 Free PMC article.
Fiducial-less alignment of cryo-sections.
Castaño-Díez D, Al-Amoudi A, Glynn AM, Seybert A, Frangakis AS. Castaño-Díez D, et al. J Struct Biol. 2007 Sep;159(3):413-23. doi: 10.1016/j.jsb.2007.04.014. Epub 2007 Jun 9. J Struct Biol. 2007. PMID: 17651988
50 results