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Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
International Consortium for Blood Pressure Genome-Wide Association Studies; Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND; CARDIoGRAM consortium; CKDGen Consortium; KidneyGen Consortium; EchoGen consortium; CHARGE-HF consortium; Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hi… See abstract for full author list ➔ International Consortium for Blood Pressure Genome-Wide Association Studies, et al. Nature. 2011 Sep 11;478(7367):103-9. doi: 10.1038/nature10405. Nature. 2011. PMID: 21909115 Free PMC article.
Lipoprotein subclass profiling reveals pleiotropy in the genetic variants of lipid risk factors for coronary heart disease: a note on Mendelian randomization studies.
Würtz P, Kangas AJ, Soininen P, Lehtimäki T, Kähönen M, Viikari JS, Raitakari OT, Järvelin MR, Davey Smith G, Ala-Korpela M. Würtz P, et al. J Am Coll Cardiol. 2013 Nov 12;62(20):1906-8. doi: 10.1016/j.jacc.2013.07.085. Epub 2013 Sep 18. J Am Coll Cardiol. 2013. PMID: 24055740 Free article. No abstract available.
Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque.
Fan YM, Hernesniemi J, Oksala N, Levula M, Raitoharju E, Collings A, Hutri-Kähönen N, Juonala M, Marniemi J, Lyytikäinen LP, Seppälä I, Mennander A, Tarkka M, Kangas AJ, Soininen P, Salenius JP, Klopp N, Illig T, Laitinen T, Ala-Korpela M, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T. Fan YM, et al. Sci Rep. 2014 Apr 11;4:4650. doi: 10.1038/srep04650. Sci Rep. 2014. PMID: 24722012 Free PMC article.
Lipoprotein subclass metabolism in nonalcoholic steatohepatitis.
Männistö VT, Simonen M, Soininen P, Tiainen M, Kangas AJ, Kaminska D, Venesmaa S, Käkelä P, Kärjä V, Gylling H, Ala-Korpela M, Pihlajamäki J. Männistö VT, et al. J Lipid Res. 2014 Dec;55(12):2676-84. doi: 10.1194/jlr.P054387. Epub 2014 Oct 24. J Lipid Res. 2014. PMID: 25344588 Free PMC article.
Interactions between genetic variants and dietary lipid composition: effects on circulating LDL cholesterol in children.
Ahola-Olli AV, Pitkänen N, Kettunen J, Oikonen MK, Mikkilä V, Lehtimäki T, Kähönen M, Pahkala K, Niinikoski H, Kangas AJ, Soininen P, Ala-Korpela M, Viikari JS, Rönnemaa T, Simell O, Raitakari OT. Ahola-Olli AV, et al. Am J Clin Nutr. 2014 Dec;100(6):1569-77. doi: 10.3945/ajcn.114.085027. Epub 2014 Oct 8. Am J Clin Nutr. 2014. PMID: 25411292 Free article. Clinical Trial.
Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.
Würtz P, Wang Q, Kangas AJ, Richmond RC, Skarp J, Tiainen M, Tynkkynen T, Soininen P, Havulinna AS, Kaakinen M, Viikari JS, Savolainen MJ, Kähönen M, Lehtimäki T, Männistö S, Blankenberg S, Zeller T, Laitinen J, Pouta A, Mäntyselkä P, Vanhala M, Elliott P, Pietiläinen KH, Ripatti S, Salomaa V, Raitakari OT, Järvelin MR, Smith GD, Ala-Korpela M. Würtz P, et al. PLoS Med. 2014 Dec 9;11(12):e1001765. doi: 10.1371/journal.pmed.1001765. eCollection 2014 Dec. PLoS Med. 2014. PMID: 25490400 Free PMC article.
266 results