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Modulation of trophoblast function by concurrent hyperglycemia and antiphospholipid antibodies is in part TLR4-dependent.
Am J Reprod Immunol. 2018 Oct;80(4):e13045. doi: 10.1111/aji.13045. Epub 2018 Sep 8.
Am J Reprod Immunol. 2018.
PMID: 30194878
Excess glucose induce trophoblast inflammation and limit cell migration through HMGB1 activation of Toll-Like receptor 4.
Heim KR, Mulla MJ, Potter JA, Han CS, Guller S, Abrahams VM.
Heim KR, et al.
Am J Reprod Immunol. 2018 Nov;80(5):e13044. doi: 10.1111/aji.13044. Epub 2018 Sep 2.
Am J Reprod Immunol. 2018.
PMID: 30175447
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