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Cytoplasmic sequestration of p27 via AKT phosphorylation in renal cell carcinoma.
Kim J, Jonasch E, Alexander A, Short JD, Cai S, Wen S, Tsavachidou D, Tamboli P, Czerniak BA, Do KA, Wu KJ, Marlow LA, Wood CG, Copland JA, Walker CL. Kim J, et al. Among authors: alexander a. Clin Cancer Res. 2009 Jan 1;15(1):81-90. doi: 10.1158/1078-0432.CCR-08-0170. Clin Cancer Res. 2009. PMID: 19118035 Free PMC article.
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL. Alexander A, et al. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4153-8. doi: 10.1073/pnas.0913860107. Epub 2010 Feb 16. Proc Natl Acad Sci U S A. 2010. PMID: 20160076 Free PMC article.
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Zhang J, Kim J, Alexander A, Cai S, Tripathi DN, Dere R, Tee AR, Tait-Mulder J, Di Nardo A, Han JM, Kwiatkowski E, Dunlop EA, Dodd KM, Folkerth RD, Faust PL, Kastan MB, Sahin M, Walker CL. Zhang J, et al. Among authors: alexander a. Nat Cell Biol. 2013 Oct;15(10):1186-96. doi: 10.1038/ncb2822. Epub 2013 Aug 18. Nat Cell Biol. 2013. PMID: 23955302 Free PMC article.
ATM functions at the peroxisome to induce pexophagy in response to ROS.
Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL. Zhang J, et al. Among authors: alexander a. Nat Cell Biol. 2015 Oct;17(10):1259-1269. doi: 10.1038/ncb3230. Epub 2015 Sep 7. Nat Cell Biol. 2015. PMID: 26344566 Free PMC article.
Cyclin E Overexpression Sensitizes Triple-Negative Breast Cancer to Wee1 Kinase Inhibition.
Chen X, Low KH, Alexander A, Jiang Y, Karakas C, Hess KR, Carey JPW, Bui TN, Vijayaraghavan S, Evans KW, Yi M, Ellis DC, Cheung KL, Ellis IO, Fu S, Meric-Bernstam F, Hunt KK, Keyomarsi K. Chen X, et al. Among authors: alexander a. Clin Cancer Res. 2018 Dec 15;24(24):6594-6610. doi: 10.1158/1078-0432.CCR-18-1446. Epub 2018 Sep 4. Clin Cancer Res. 2018. PMID: 30181387 Free PMC article.
1,915 results