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Mitochondrial health is enhanced in rats with higher vs. lower intrinsic exercise capacity and extended lifespan.
Aon MA, Cortassa S, Juhaszova M, González-Reyes JA, Calvo-Rubio M, Villalba JM, Lachance AD, Ziman BD, Mitchell SJ, Murt KN, Axsom JEC, Alfaras I, Britton SL, Koch LG, de Cabo R, Lakatta EG, Sollott SJ. Aon MA, et al. Among authors: alfaras i. NPJ Aging Mech Dis. 2021 Jan 4;7(1):1. doi: 10.1038/s41514-020-00054-3. NPJ Aging Mech Dis. 2021. PMID: 33398019 Free PMC article.
Health benefits of late-onset metformin treatment every other week in mice.
Alfaras I, Mitchell SJ, Mora H, Lugo DR, Warren A, Navas-Enamorado I, Hoffmann V, Hine C, Mitchell JR, Le Couteur DG, Cogger VC, Bernier M, de Cabo R. Alfaras I, et al. NPJ Aging Mech Dis. 2017 Nov 20;3:16. doi: 10.1038/s41514-017-0018-7. eCollection 2017. NPJ Aging Mech Dis. 2017. PMID: 29167747 Free PMC article.
Pharmacological Strategies to Retard Cardiovascular Aging.
Alfaras I, Di Germanio C, Bernier M, Csiszar A, Ungvari Z, Lakatta EG, de Cabo R. Alfaras I, et al. Circ Res. 2016 May 13;118(10):1626-42. doi: 10.1161/CIRCRESAHA.116.307475. Circ Res. 2016. PMID: 27174954 Free PMC article. Review.
Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques.
Palliyaguru DL, Vieira Ligo Teixeira C, Duregon E, di Germanio C, Alfaras I, Mitchell SJ, Navas-Enamorado I, Shiroma EJ, Studenski S, Bernier M, Camandola S, Price NL, Ferrucci L, de Cabo R. Palliyaguru DL, et al. Among authors: alfaras i. J Gerontol A Biol Sci Med Sci. 2021 Mar 31;76(4):552-560. doi: 10.1093/gerona/glaa285. J Gerontol A Biol Sci Med Sci. 2021. PMID: 33211821 Free PMC article.
Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.
Bernier M, Wahl D, Ali A, Allard J, Faulkner S, Wnorowski A, Sanghvi M, Moaddel R, Alfaras I, Mattison JA, Tarantini S, Tucsek Z, Ungvari Z, Csiszar A, Pearson KJ, de Cabo R. Bernier M, et al. Among authors: alfaras i. Aging (Albany NY). 2016 May;8(5):899-916. doi: 10.18632/aging.100942. Aging (Albany NY). 2016. PMID: 27070252 Free PMC article.
GH Receptor Deficiency in Ecuadorian Adults Is Associated With Obesity and Enhanced Insulin Sensitivity.
Guevara-Aguirre J, Rosenbloom AL, Balasubramanian P, Teran E, Guevara-Aguirre M, Guevara C, Procel P, Alfaras I, De Cabo R, Di Biase S, Narvaez L, Saavedra J, Longo VD. Guevara-Aguirre J, et al. Among authors: alfaras i. J Clin Endocrinol Metab. 2015 Jul;100(7):2589-96. doi: 10.1210/jc.2015-1678. Epub 2015 May 18. J Clin Endocrinol Metab. 2015. PMID: 25985182 Free PMC article.
Muscle cannabinoid 1 receptor regulates Il-6 and myostatin expression, governing physical performance and whole-body metabolism.
González-Mariscal I, Montoro RA, O'Connell JF, Kim Y, Gonzalez-Freire M, Liu QR, Alfaras I, Carlson OD, Lehrmann E, Zhang Y, Becker KG, Hardivillé S, Ghosh P, Egan JM. González-Mariscal I, et al. Among authors: alfaras i. FASEB J. 2019 May;33(5):5850-5863. doi: 10.1096/fj.201801145R. Epub 2019 Feb 6. FASEB J. 2019. PMID: 30726112 Free PMC article.
21 results