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B-cell-directed CAR-T cell therapy activates CD8+ cytotoxic CARneg bystander T-cells in non-human primates and patients.
Kaminski J, Fleming RA, Alvarez-Calderon F, Winschel MB, McGuckin C, Ho EE, Eng F, Rui X, Keskula P, Cagnin L, Charles J, Zavistaski JM, Margossian SP, Kapadia M, Rottman JB, Lane J, Baumeister SHC, Tkachev V, Shalek A, Kean LS, Gerdemann U. Kaminski J, et al. Among authors: alvarez calderon f. Blood. 2024 Apr 1:blood.2023022717. doi: 10.1182/blood.2023022717. Online ahead of print. Blood. 2024. PMID: 38558106
Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice.
Saha A, Palchaudhuri R, Lanieri L, Hyzy S, Riddle MJ, Panthera J, Eide C, Tolar J, Panoskaltsis-Mortari A, Gorfinkel L, Tkachev V, Gerdemann U, Alvarez-Calderon F, Palato ER, MacMillan ML, Wagner JE, Kean LS, Osborn M, Kiem HP, Scadden DT, Olson LM, Blazar BR. Saha A, et al. Among authors: alvarez calderon f. Blood. 2024 Mar 6:blood.2023023549. doi: 10.1182/blood.2023023549. Online ahead of print. Blood. 2024. PMID: 38447038
Real-world experience with low-dose IL-2 for children and young adults with refractory chronic graft-versus-host disease.
Wobma H, Kapadia M, Kim HT, Alvarez-Calderon F, Baumeister SHC, Duncan C, Forrest S, Gorfinkel L, Huang J, Lehmann LE, Li H, Schwartz M, Koreth J, Ritz J, Kean LS, Whangbo JS. Wobma H, et al. Among authors: alvarez calderon f. Blood Adv. 2023 Aug 22;7(16):4647-4657. doi: 10.1182/bloodadvances.2023009729. Blood Adv. 2023. PMID: 37603347 Free PMC article.
Uncovering CD4+ T-cell exhaustion in B-ALL.
Gerdemann U, Alvarez-Calderon F. Gerdemann U, et al. Among authors: alvarez calderon f. Blood. 2022 Jul 28;140(4):294-296. doi: 10.1182/blood.2022016597. Blood. 2022. PMID: 35900788 Free article. No abstract available.
ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.
Gregory MA, D'Alessandro A, Alvarez-Calderon F, Kim J, Nemkov T, Adane B, Rozhok AI, Kumar A, Kumar V, Pollyea DA, Wempe MF, Jordan CT, Serkova NJ, Tan AC, Hansen KC, DeGregori J. Gregory MA, et al. Among authors: alvarez calderon f. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6669-E6678. doi: 10.1073/pnas.1603876113. Epub 2016 Oct 10. Proc Natl Acad Sci U S A. 2016. PMID: 27791036 Free PMC article.
Oncogenic drivers and mitochondrial dependency.
Alvarez-Calderon F, DeGregori J. Alvarez-Calderon F, et al. Aging (Albany NY). 2015 Mar;7(3):148-9. doi: 10.18632/aging.100734. Aging (Albany NY). 2015. PMID: 25868642 Free PMC article. No abstract available.
15 results